Debate: To Statin or Not to Statin (in Healthy Women)
the MPR take:
Are women benefiting from statin therapy? Several studies suggest they may not be, and that rather than helping prevent heart attacks, statin use in healthy women may actually be contributing to other health problems such as diabetes. Part of the problem lies in the fact that women do not make up the majority of the population in statin trials, so it can be difficult to assess benefit/risk since the evidence is so limited. While some clinicians believe there is no benefit, others aren't quick to dismiss the use of these drugs in the female population, citing that having little data does not necessarily mean the drugs aren't helpful. The recent update to the ACC/AHA cholesterol guidelines further fuels this debate since the new guidelines significantly increase the number of patients who fall into the criteria for statin therapy.
Should so many women be taking statins. “If you're going to tell a healthy person to take a medicine every day for the rest of their life, you should have really good data that it's going to make them better off,” said Dr. Lowering cholesterol should not be not an end in itself, she added, and ...
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