Celiac Disease Prevalence Is Less Than 1% in the U.S.
(HealthDay News) – The prevalence of celiac disease in the United States is 0.71%.
Alberto Rubio-Tapia, MD, from the Mayo Clinic in Rochester, MN, and colleagues analyzed data from 7,798 persons (aged >6 years) who participated in the National Health and Nutrition Examination Survey 2009–2010. All participants' serum samples were tested for immunoglobulin A (IgA) tissue transglutaminase antibodies and, if results were abnormal, also for IgA endomysial antibodies. Interviews determined information about prior diagnosis of celiac disease and use of a gluten-free diet (GFD). Celiac disease was defined as having either a double-positive serological diagnosis or a reported physician diagnosis and being on a GFD
The researchers found that celiac disease was detected in 35 participants (20 were women and 29 were non-Hispanic white), 29 of whom were unaware of their diagnosis, for a prevalence of celiac disease in the United States of 0.71 percent (95% confidence interval [CI], 0.58–0.86%), and a prevalence of 1.01% (95% CI, 0.78–1.31%) among non-Hispanic whites. Fifty-five participants reported following a GFD, which corresponded to a prevalence of 0.63 percent (95% CI, 0.36–1.07%).
"The prevalence of celiac disease in the United States was 0.71%, similar to that found in several European countries," the authors write.