Caffeine During Pregnancy Could Increase Obesity Risk in Offspring
the MPR take:
Caffeine intake during pregnancy has been linked to an increased risk of miscarriage, fetal death, and neurological impairment in offspring, and a new study has also found an association between in-utero exposure to caffeine and an increased risk of childhood obesity. In research appearing in the International Journal of Obesity, 829 women who delivered a live-born infant were evaluated for maternal caffeine consumption during pregnancy and their offspring were tracked longitudinally from birth until either the offspring left the participating healthcare system or the end of the study period, with over 15 years of follow-up for those who remained in the system until the end of the study. After controlling for various factors, overall caffeine exposure during pregnancy was linked to an 87% increased risk of childhood obesity. For women who consumed >150mg/day of caffeine, the risk of childhood obesity more than doubled. Each one unit increase (log10 scale) in the amount of maternal caffeine intake was associated with a 23% increased risk of offspring obesity. This observed relationship appeared to be stronger among those with persistent vs. transitory obesity and among girls vs. boys. All sources of caffeine (coffee, soda, tea, etc) had similar associations with the risk of childhood obesity. If these results are confirmed in future research, encouraging pregnant women to limit or eliminate caffeine consumption could be a step towards preventing childhood obesity.
In-utero exposures through adverse fetal programming are emerging as an important contributing factor to the epidemic of childhood obesity. This study examines the impact of in-utero exposure to caffeine on the risk of childhood obesity in offspring. Maternal caffeine intake was prospectively ...
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