Breast Cancer Gene Linked to High-Risk Uterine Cancer
the MPR take:
Women with BRCA1 mutations have a greater risk of developing rare, aggressive forms of uterine cancer, even after salpingo-oophorectomy. The findings, presented at the Society of Gynecologic Oncology Annual Meeting on Women’s Cancer, studied 525 women with BRCA mutations undergoing risk-reducing salpingo-oophorectomy without concomitant hysterectomy. These women had a 2.1% increased risk for high-risk uterine cancers within 10 years after salpingo-oophorectomy–26 times the risk of the general population. No women in the study were diagnosed with low-risk uterine cancers.
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