Abdominal Obesity: Strong VTE Risk Factor, Review Suggests
the MPR take:
It is believed that metabolic syndrome (MetS) may contribute to the pathogenesis of venous thromboembolism (VTE), but a new study has found MetS to be independently associated with VTE with abdominal adiposity as a strong risk factor for VTE. The review, published in the journal Arteriosclerosis, Thrombosis, and Vascular Biology, was a meta-analysis of both case-control and cohort studies evaluating MetS and risk of unprovoked VTE. MetS was found to be independently associated with VTE (odds ratio, 1.91; 95% CI, 1.57–2.33), with MetS and abdominal obesity as superior predictors of unprovoked VTE compared to obesity defined by body mass index (BMI). In two prospective cohort studies, age, obesity, and abdominal obesity were associated with VTE but not MetS. Although additional research is needed to further examine the MetS-VTE association, currently studies indicate that abdominal adiposity is a strong risk factor for VTE.
Objective- The metabolic syndrome (MetS) may contribute to the pathogenesis of venous thromboembolism (VTE), but this association requires additional investigation. For case-control studies, odds ratios and 95% confidence intervals were calculated using logistic regression analysis to estimate ...
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