AACR: Sedentary Time Linked to CR Adenoma Recurrence in Men
(HealthDay News) – For men, sedentary time is positively associated with the risk of colorectal adenoma recurrence, according to a study presented at the American Association for Cancer Research's International Conference on Frontiers in Cancer Prevention Research, held from Oct. 27–30 in National Harbor, MD.
Christine L. Sardo Molmenti, PhD, MPH, from the Columbia University Mailman School of Public Health in New York City, and colleagues used data from a pooled sample of 1,730 participants from the Wheat Bran Fiber and Ursodeoxycholic Acid Phase 3 trial to examine the correlation between sedentary, recreational, and household activity and colorectal adenoma recurrence.
The researchers observed no significant correlation between any activity type and colorectal adenoma recurrence overall. However, the odds of adenoma recurrence were significantly higher (45%) for males with the highest sedentary time. Compared with the lowest quartile of sedentary activity, the odds ratios were 1.31 for the second quartile, 1.47 for the third quartile, and 1.45 for the fourth quartile (P trend=0.03). An increased risk of recurrent adenoma was also seen for men with low recreational activity and high sedentary time (odds ratio, 1.41) compared with the reference group (low sedentary time/low recreational activity).
"Given the substantial increase in risk of colorectal adenoma recurrence we observed for men with the highest sedentary time, we believe it would be beneficial to see 'reduce prolonged sitting time' added to the list of public health recommendations currently in place for health promotion and disease prevention," Molmenti said in a statement.