MAXZIDE Rx

Select the drug indication to add to your list

MAXZIDE

Edema
Hypertension
Only 4 drugs may be compared at once

Generic Name and Formulations:

Triamterene 75mg, hydrochlorothiazide 50mg; scored tabs.

Company:

Mylan Inc.

Select therapeutic use:

Indications for MAXZIDE:

Edema.

Adult:

Initially one Maxzide-25mg tab/day. Usual dosage: 1–2 Maxzide-25mg tabs or one Maxzide tab once daily. As a substitute for triamterene 50–100mg/day and hydrochlorothiazide 25–50mg/day in less bioavailable form, give one Maxzide-25mg tab/day.

Children:

Not recommended.

Contraindications:

Hyperkalemia. Renal impairment. Anuria. Sulfonamide allergy. Concomitant potassium or K+-sparing diuretics.

Warnings/Precautions:

Diabetes. Acidosis predisposition. Electrolyte imbalance. Excessive diuresis. History of renal stones. Gout. Asthma. SLE. Surgery. Monitor electrolytes, renal function. Discontinue if serum potassium >5.5mEq/L or <3mEq/L. Hepatic impairment: monitor for hepatic coma, if confusion increases, discontinue for a few days. Elderly. Severely ill. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Digitalis, lithium toxicity. Adjust antidiabetic, antigout medications. Hyperkalemia more likely with ACE inhibitors. NSAIDs may cause renal failure. Hypokalemia with corticosteroids, ACTH, amphotericin B. Hypotension with CNS depressants. Potentiates other antihypertensives, nondepolarizing muscle relaxants. Antagonized by NSAIDs. Hyponatremia with sulfonylureas. Antagonizes folic acid. May block epinephrine. May interfere with parathyroid tests.

See Also:

MAXZIDE-25mg

Pharmacological Class:

K+-sparing + thiazide.

Adverse Reactions:

Drowsiness, insomnia, muscle cramps, weakness, headache, GI disturbances, dizziness, orthostatic hypotension, hyperuricemia, impotence, renal stones, tachycardia, dyspnea, dry mouth, depression, anxiety, urine discoloration, elevated liver enzymes.

How Supplied:

Tabs—100, 500

MAXZIDE 75mg/50mg tablets (Qty:30)

appx. price $115.00

Indications for MAXZIDE:

Hypertension when normokalemia is essential.

Adult:

1 tab daily.

Children:

Not recommended.

Contraindications:

Hyperkalemia. Renal impairment. Anuria. Sulfonamide allergy. Concomitant potassium or K+-sparing diuretics.

Warnings/Precautions:

Diabetes. Acidosis predisposition. Electrolyte imbalance. Excessive diuresis. History of renal stones. Gout. Asthma. SLE. Surgery. Monitor electrolytes, renal function. Discontinue if serum potassium >5.5mEq/L or <3mEq/L. Hepatic impairment: monitor for hepatic coma, if confusion increases, discontinue for a few days. Elderly. Severely ill. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Digitalis, lithium toxicity. Adjust antidiabetic, antigout medications. Hyperkalemia more likely with ACE inhibitors. NSAIDs may cause renal failure. Hypokalemia with corticosteroids, ACTH, amphotericin B. Hypotension with CNS depressants. Potentiates other antihypertensives, nondepolarizing muscle relaxants. Antagonized by NSAIDs. Hyponatremia with sulfonylureas. Antagonizes folic acid. May block epinephrine. May interfere with parathyroid tests.

See Also:

MAXZIDE-25mg

Pharmacological Class:

Diuretic combination.

Adverse Reactions:

Drowsiness, insomnia, muscle cramps, weakness, headache, GI disturbances, dizziness, orthostatic hypotension, hyperuricemia, impotence, renal stones, tachycardia, dyspnea, dry mouth, depression, anxiety, urine discoloration, elevated liver enzymes.

How Supplied:

Tabs—100, 500

MAXZIDE 75mg/50mg tablets (Qty:30)

appx. price $115.00