LUPRON DEPOT 3.75mg Rx

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LUPRON DEPOT 3.75mg

Anemias
Endometriosis
Miscellaneous Ob/Gyn conditions
Only 4 drugs may be compared at once

Generic Name and Formulations:

Leuprolide acetate 3.75mg; depot susp for IM inj; preservative-free.

Company:

AbbVie

Select therapeutic use:

Indications for LUPRON DEPOT 3.75mg:

Presurgical treatment of patients with anemia due to uterine leiomyomata (fibroids), with iron therapy if iron therapy alone is inadequate.

Adult:

≥18yrs: 3.75mg IM once per month for up to 3 months.

Children:

<18yrs: not applicable.

Contraindications:

Undiagnosed abnormal vaginal bleeding. Pregnancy (Cat.X). Nursing mothers.

Warnings/Precautions:

Exclude pregnancy before starting; use nonhormonal contraception during therapy; discontinue if pregnancy occurs. Risk factors for decreased bone mineral density (eg, chronic alcohol, tobacco, anticonvulsants, corticosteroids). Missing successive doses may cause breakthrough bleeding or ovulation. Elderly.

See Also:

LUPRON DEPOT-3 MONTH 11.25mg

Pharmacological Class:

GnRH analogue.

Adverse Reactions:

Hot flashes, headache, vaginitis, depression, emotional lability, pain, decreased libido, breast changes, amenorrhea, mastodynia, joint disorder, asthenia, GI upset, edema, bone density loss, local reactions, acne, memory disorders, others; rarely: anaphylaxis, asthma, increased serum transaminases or lipids.

How Supplied:

Kit—1 (single-dose syringe w. diluent, supplies)

Indications for LUPRON DEPOT 3.75mg:

Endometriosis management, including pain relief and reduction of endometriotic lesions. With norethindrone acetate: for initial management and recurrent symptoms.

Adult:

≥18yrs: 3.75mg IM once per month for up to 6 months. May repeat one 6-month cycle; give with norethindrone acetate 5mg daily when retreating.

Children:

<18yrs: not applicable (unless endometriosis occurs after puberty; see full labeling).

Contraindications:

Undiagnosed abnormal vaginal bleeding. Pregnancy (Cat.X). Nursing mothers.

Warnings/Precautions:

Exclude pregnancy before starting; use nonhormonal methods of contraception during therapy; discontinue if pregnancy occurs. Consider concomitant norethindrone acetate and supplemental calcium with risk factors for decreased bone mineral density (eg, chronic alcohol, tobacco, anticonvulsants, corticosteroids). Missing successive doses may cause breakthrough bleeding or ovulation. Retreatment: not recommended.

See Also:

LUPRON DEPOT-3 MONTH 11.25mg

Pharmacological Class:

GnRH analogue.

Adverse Reactions:

Hot flashes, headache, vaginitis, depression, emotional lability, pain, decreased libido, breast changes, amenorrhea, mastodynia, joint disorder, asthenia, GI upset, edema, bone density loss, local reactions, acne, memory disorders, others; rarely: anaphylaxis, asthma, increased serum transaminases or lipids.

How Supplied:

Kit—1 (single-dose syringe w. diluent, supplies)

Indications for LUPRON DEPOT 3.75mg:

Presurgical treatment of patients with anemia due to uterine leiomyomata (fibroids), with iron therapy if iron therapy alone is inadequate.

Adult:

≥18yrs: 3.75mg IM once per month for up to 3 months.

Children:

<18yrs: not applicable.

Contraindications:

Undiagnosed abnormal vaginal bleeding. Pregnancy (Cat.X). Nursing mothers.

Warnings/Precautions:

Exclude pregnancy before starting; use nonhormonal contraception during therapy; discontinue if pregnancy occurs. Risk factors for decreased bone mineral density (eg, chronic alcohol, tobacco, anticonvulsants, corticosteroids). Missing successive doses may cause breakthrough bleeding or ovulation. Elderly.

See Also:

LUPRON DEPOT-3 MONTH 11.25mg

Pharmacological Class:

GnRH analogue.

Adverse Reactions:

Hot flashes, headache, vaginitis, depression, emotional lability, pain, decreased libido, breast changes, amenorrhea, mastodynia, joint disorder, asthenia, GI upset, edema, bone density loss, local reactions, acne, memory disorders, others; rarely: anaphylaxis, asthma, increased serum transaminases or lipids.

How Supplied:

Kit—1 (single-dose syringe w. diluent, supplies)