LORYNA Rx

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LORYNA

Acne
Contraception
Only 4 drugs may be compared at once

Generic Name and Formulations:

Drospirenone 3mg, ethinyl estradiol 20micrograms (24 tabs); inert (4 tabs).

Company:

Sandoz

Select therapeutic use:

Indications for LORYNA:

Moderate acne vulgaris in females ≥14 years of age, who have no known contraindications to oral contraceptive therapy, have achieved menarche, and desire contraception.

Adult:

1 tab daily for 28 days; repeat.

Children:

Not applicable.

Contraindications:

Thrombophlebitis or thromboembolic disorders. Cerebral vascular or coronary artery disease. Renal, hepatic, or adrenal insufficiency. Severe hypertension. Valvular heart disease. Diabetes with vascular involvement. Headaches with focal neurological symptoms. Major surgery with prolonged immobilization. Heavy smoking (>15 cigarettes per day) and over age 35. Breast or other estrogen-dependent neoplasms. Undiagnosed abnormal genital bleeding. Cholestatic jaundice of pregnancy or jaundice with prior OC use. Hepatic adenoma or carcinoma. Pregnancy (Cat.X).

Warnings/Precautions:

Hypertriglyceridemia. Discontinue if jaundice, visual disturbances, migraine or other severe headaches occur. Do regular complete physical exams. May need barrier contraception with Sunday starts or postpartum use (see literature). Monitor K+ during 1st cycle if risk of hyperkalemia. Nursing mothers: not recommended.

Interactions:

Antagonized by hepatic enzyme inducing drugs (eg, rifampin, griseofulvin, St. John's wort), possibly others. May affect measurement of sex hormone-binding globulin levels. Monitor K+ during 1st cycle with drugs that increase potassium (eg, ACE inhibitors, angiotensin receptor blockers, NSAIDs, K+ sparing diuretics).

Pharmacological Class:

Progestin + estrogen.

Adverse Reactions:

Hypertension, nausea, vomiting, breakthrough bleeding, amenorrhea, transient delay of ovulation after discontinuation, edema, chloasma, mastodynia, headache, intolerance to contact lenses. Increased risk of gallbladder disease, thromboembolic disorders.

How Supplied:

Packs—3

LORYNA 28 tablets of 3mg/0.02mg packages (Qty:1)

appx. price $112.00

Indications for LORYNA:

Oral contraception.

Adult:

1 tab daily for 28 days; repeat.

Children:

Not applicable.

Contraindications:

Thrombophlebitis or thromboembolic disorders. Cerebral vascular or coronary artery disease. Renal, hepatic, or adrenal insufficiency. Severe hypertension. Valvular heart disease. Diabetes with vascular involvement. Headaches with focal neurological symptoms. Major surgery with prolonged immobilization. Heavy smoking (>15 cigarettes per day) and over age 35. Breast or other estrogen-dependent neoplasms. Undiagnosed abnormal genital bleeding. Cholestatic jaundice of pregnancy or jaundice with prior OC use. Hepatic adenoma or carcinoma. Pregnancy (Cat.X).

Warnings/Precautions:

Hypertriglyceridemia. Discontinue if jaundice, visual disturbances, migraine or other severe headaches occur. Do regular complete physical exams. May need barrier contraception with Sunday starts or postpartum use (see literature). Monitor K+ during 1st cycle if risk of hyperkalemia. Nursing mothers: not recommended.

Interactions:

Antagonized by hepatic enzyme inducing drugs (eg, rifampin, griseofulvin, St. John's wort), possibly others. May affect measurement of sex hormone-binding globulin levels. Monitor K+ during 1st cycle with drugs that increase potassium (eg, ACE inhibitors, angiotensin receptor blockers, NSAIDs, K+ sparing diuretics).

Pharmacological Class:

Progestin + estrogen.

Adverse Reactions:

Hypertension, nausea, vomiting, breakthrough bleeding, amenorrhea, transient delay of ovulation after discontinuation, edema, chloasma, mastodynia, headache, intolerance to contact lenses. Increased risk of gallbladder disease, thromboembolic disorders.

How Supplied:

Packs—3

LORYNA 28 tablets of 3mg/0.02mg packages (Qty:1)

appx. price $112.00