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LAMISIL TABLETS

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Generic Name for LAMISIL TABLETS

Terbinafine (as HCl) 250mg.

Legal Classification:

Rx

Pharmacological Class for LAMISIL TABLETS

Allylamine.

Manufacturer of LAMISIL TABLETS

Novartis Pharmaceuticals Corp

Indications for LAMISIL TABLETS

Onychomycosis of the toenail or fingernail due to tinea unguium.

Adult dose for LAMISIL TABLETS

≥18 years: 250mg once daily for 6 weeks (fingernail) or 12 weeks (toenail).

Children's dosing for LAMISIL TABLETS

<18 years: not recommended.

Also:

Warnings/Precautions for LAMISIL TABLETS

Onychomycosis: confirm diagnosis with nail specimen. Do baseline liver function test. Pre-existing hepatic disease or renal impairment (CrCl <50mL/min): not recommended. Discontinue if hepatobiliary dysfunction, progressive skin rash (eg, Stevens-Johnson syndrome, toxic epidermal necrolysis), or severe neutropenia occurs. Monitor CBCs if immunodeficient. Pregnancy (Cat.B), nursing mothers: not recommended.

Interactions for LAMISIL TABLETS

Potentiated by cimetidine. Antagonized by rifampin. May potentiate drugs metabolized by CYP2D6. May be potentiated by CYP2C9 and CYP3A4 inhibitors (eg, fluconazole, ketoconazole, amiodarone). Monitor cyclosporine.

Adverse Reactions for LAMISIL TABLETS

GI disturbances, liver test abnormalities, rash, pruritus, taste disturbances, urticaria; also children: nasopharyngitis, headache, pyrexia, cough, upper respiratory infection; rare: hepatotoxicity, liver failure, lupus erythematosus.

How is LAMISIL TABLETS supplied?

Tabs—30, 100; Packets—14, 42

Related Disease:

Infections, fungal~systemic antifungals
Onychomycosis~systemic antifungals

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