Labetalol HCl Tablets Rx

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Labetalol HCl Tablets

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Generic Name and Formulations:

Labetalol HCl 100mg, 200mg, 300mg; scored tabs.

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Indications for Labetalol HCl Tablets:



Individualize. Initially 100mg twice daily. Titrate at 2–3 day intervals in increments of 100mg twice daily. Usual maintenance: 200–400mg twice daily; max 2.4g/day.


Not recommended.


Usual maintenance: 100–200mg twice daily.


Asthma. 2nd- or 3rd-degree AV block. Overt cardiac failure. Cardiogenic shock. Severe bradycardia, other conditions associated with prolonged or severe hypotension.


History of heart failure; withdraw gradually if cardiac failure continues despite adequate digitalization and diuretic. Monitor hepatic function; discontinue at first sign of liver injury. COPD. Pheochromocytoma. Diabetes. Surgery. Avoid abrupt cessation (ischemic heart disease may be exacerbated). Elderly. Pregnancy (Cat.C). Nursing mothers.


Caution with verapamil. Potentiates hypotension with nitroglycerin. May block epinephrine, β-agonist bronchodilators. Adjust antidiabetic medication. Potentiated by cimetidine. Tremor with tricyclic antidepressants. Synergism with halothane; do not use high concentrations.

Pharmacological Class:

Noncardioselective beta-blocker/alpha-1 blocker.

Adverse Reactions:

Dizziness, GI upset, fatigue, nasal stuffiness, ejaculation failure, headache, dyspnea, vertigo, rash, orthostatic hypotension, edema, heart failure, bronchospasm, jaundice.


Formerly known under the brand names Normodyne, Trandate.

How Supplied:

Contact supplier.