KLONOPIN

Generic Name for KLONOPIN Clonazepam 0.5mg+, 1mg, 2mg; tabs; +scored. Legal Classification: CIV Pharmacological Class for KLONOPIN Benzodiazepine. Manufacturer of KLONOPIN Roche Laboratories

Indications for KLONOPIN

Panic disorder.

Adult dose for KLONOPIN

>18yrs: initially 0.25mg twice daily; after 3 days increase to 1mg/day; then may increase every 3 days by 0.125–0.25mg twice daily; max 4mg/day. Wafers: dissolve in mouth; swallow with or without water.

Children's dosing for KLONOPIN

<18yrs: not recommended.

Also:

Contraindications for KLONOPIN

Significant liver disease. Acute narrow-angle glaucoma.

Precautions for KLONOPIN

Suicidal tendencies (monitor). Chronic respiratory disease. Renal impairment. Avoid abrupt cessation. Reevaluate periodically. Monitor blood counts, liver function. Elderly. Labor & delivery, pregnancy (Cat.D), nursing mothers: not recommended.

Interactions for KLONOPIN

Potentiates CNS depression with alcohol, other CNS depressants. Adjust anticonvulsants if needed. Absence seizures with valproate. Caution with drugs that inhibit CYP3A (eg, azole antifungals). Antagonized by CYP450 inducers (eg, phenytoin, carbamazepine, phenobarbital). Wafers may be antagonized by propantheline.

Adverse Reactions for KLONOPIN

CNS effects (esp. depression), hypersalivation, liver disorders, GI upset, blood dyscrasias, paradoxical reactions.

How is KLONOPIN supplied?

Tabs—100
Wafers—60