Ketorolac Tablets Rx

Adult Dose for Ketorolac Tablets:

Use tabs only as continuation therapy to inj. Do not exceed 5 days' combined (inj + tabs) therapy or recommended dose (may use as-needed opioids for breakthrough pain if appropriate). After inj therapy: 16–65yrs (normal renal function): 20mg once then 10mg every 4–6 hours; max 40mg/day. ≥65yrs, or <110lbs, or renal impairment: 10mg every 4–6 hours; max 40mg/day.

Children's Dose for Ketorolac Tablets:

<16yrs: not recommended.

Contraindications:

Aspirin allergy. Peptic ulcer. GI bleed or perforation. Advanced renal impairment. Hypovolemia. Pre-op or intra-operative use when hemostasis is critical. Cerebrovascular bleeding. Hemorrhagic diathesis. Incomplete hemostasis. Bleeding disorders or high risk of bleeding. Concomitant probenecid, salicylates, other NSAIDs. Epidural or intrathecal inj. Labor & delivery. Late pregnancy. Nursing mothers.

Warnings/Precautions:

Not for pre-op use. Renal or hepatic dysfunction. Discontinue if abnormal liver function tests occur. Correct hypovolemia first. Hypertension. Cardiac decompensation. Coagulation disorders. May prolong bleeding time. Asthma. Elderly. Debilitated. Children: increased risk of bleeding after tonsillectomy. Pregnancy (Cat.C).

Interactions:

See Contraindications. Monitor anticoagulants closely. Antagonizes furosemide, possibly antiepileptics. May increase serum lithium, methotrexate levels. ACEIs, diuretics increase renal toxicity risk. Hallucinations with fluoxetine, thiothixene, alprazolam. Apnea with non-depolarizing muscle relaxants.

Adverse Reactions:

Headache, GI pain/fullness, dyspepsia, other GI effects, dizziness, drowsiness, edema, inj site pain, hypertension, pruritus, rash, stomatitis, purpura, sweating, peptic ulcer, GI bleed/perforation, bleeding, renal or liver failure, anaphylaxis.

Note:

Formerly known under the brand name Toradol.

How Supplied:

Contact supplier.