For mydriasis and/or cycloplegia. For cycloplegic refraction, for papillary dilation desired in inflammatory conditions of the iris and uveal tract.
Compress lacrimal sac by digital pressure for 2–3 minutes after instillation to avoid excessive systemic absorption. Uveitis: 1–2 drops in the eye(s) up to 4 times daily. Heavily pigmented irides may require larger doses.
Primary glaucoma or tendency toward glaucoma (eg, narrow anterior chamber angle).
Previous susceptibility to belladonna alkaloids; excessive use may produce systemic symptoms of atropine poisoning. Estimate depth of angle of anterior chamber to avoid inducing angle closure glaucoma. Infants. Pregnancy (Cat.C). Nursing mothers.
Prolonged use: follicular conjunctivitis, vascular congestion, edema, exudate, eczematoid dermatitis; hypotension, progressive respiratory depression (with excessive systemic absorption); children: coma, death possible.