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IOPIDINE
Glaucoma
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Drug Name:

IOPIDINE Rx

Generic Name and Formulations:
Apraclonidine (as HCl) 0.5%; oph. soln; contains benzalkonium chloride.

Company:
Alcon Laboratories, Inc.

e-Prescribe this drug via Surescripts

Therapeutic Use:

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Indications for IOPIDINE:

Short-term adjunctive therapy to reduce elevated IOP.

Adult Dose for IOPIDINE:

1–2 drops 3 times daily. Allow at least 5min between instillation of other oph drugs.

Children's Dose for IOPIDINE:

Not recommended.

Pharmacological Class:

alpha-2 agonist.

Contraindications:

Clonidine allergy. Concomitant MAOIs.

Warnings/Precautions:

Monitor visual fields. Severe uncontrolled cardiovascular disease, hypertension, coronary insufficiency. Recent myocardial infarction. Cerebrovascular disease. Raynaud's syndrome. Thromboangiitis obliterans. Renal or hepatic impairment. Depression. Masks hypoglycemia. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Hypertensive crisis with MAOIs. May potentiate CNS depressants, alcohol. May be antagonized by tricyclic antidepressants. Additive hypotensive effects with neuroleptics; hypotensive and pulse effects with β-blockers, antihypertensives, cardiac glycosides, others (eg, clonidine).

Adverse Reactions:

Hyperemia, pruritus, dry mouth, itching, discomfort, tearing, dizziness, solmnolence, lid edema, blurred vision, foreign body sensation, dry eye, conjunctivitis, discharge, blanching, headache, asthenia, dry nose, taste perversion; tachyphylaxis may develop after 1 month.

How Supplied:

Soln—5mL, 10mL