Immunization

AAP Recommends Shot Over Nasal Spray for 2018-2019 Flu Season

By May 22, 2018

The advisory comes early as physicians are currently placing vaccine orders.

Robust Immune Responses for Herpes Zoster Subunit Vaccine

May 21, 2018

The researchers identified a humoral response in 97.8 and 2% of HZ/su and placebo recipients, respectively, after vaccination.

HPV Vaccination May Offer Protection Against Cervical Precancer

By May 11, 2018

The authors concluded, "There is high-certainty evidence that HPV vaccines protect against cervical precancer in adolescent girls and young women aged 15 to 26," while also indicated that future studies should have long-term follow-up.

Vaccine for Chikungunya Prevention Gets Fast Track Designation

By May 04, 2018

There are currently no approved treatments or vaccines available for chikungunya, a virus transmitted through mosquito bites.

Flu Vaccines Have High Impact, Even With Relatively Low Efficacy

May 01, 2018

The researchers found that even relatively low-efficacy influenza vaccines can have a high impact, especially with optimal distribution across age groups. In order to minimize mortality and DALYs, the optimal distribution of the vaccine uptake shifts toward the elderly as vaccine efficacy declines.

FDA to Review Fluzone Quadrivalent 0.5mL Dose for Younger Patients

By April 27, 2018

The sBLA included clinical data from a Phase 4 study that enrolled nearly 2000 children and assessed the safety and immunogenicity of the 0.5mL dose.

CDC: Recommendations on the Use of Heplisav-B Published

By April 23, 2018

Benefits of protection with 2 doses administered over 1 month make the vaccine an important option for prevention of HBV.

MenB Vaccine Gets Breakthrough Tx Designation for Kids Ages 1 to 9 Years

By April 23, 2018

The Breakthrough designation was based on data from Phase 2 studies which assessed the safety and efficacy of the vaccine in this patient population.

Efficacy of Adjuvanted vs Conventional Quadrivalent Flu Vaccine Compared

By April 20, 2018

MF59 adjuvanted, quadrivalent influenza vaccine (aQIV) was found to be more efficacious in preventing influenza than a non-adjuvanted conventional influenza vaccine in children aged 6 through 23 months.

Review: Treatment Recommendations for Biological Disasters

By April 17, 2018

The Centers for Disease Control and Prevention (CDC) classifies key biological agents into three categories: A, B, and C.

Personalized Cancer Vaccine Looks Promising in Early Study

By April 12, 2018

The researchers enrolled 25 platinum-pretreated, immunotherapy-naïve patients with recurrent advanced epithelial ovarian cancer (EOC) for the trial.

A Zika vaccine could virtually eliminate prenatal infections

April 11, 2018

Zika virus shown to be of moderate to high efficacy in eliminating prenatal infections.

Stronger Recommendations by PCPs for Herpes Zoster Vaccination Needed, Says Study

By April 09, 2018

From January to March 2017, the researchers distributed a cross-sectional online survey to all physicians in the Division of General Internal Medicine and Clinical Innovation at NYULH, across 5 different practice settings. A total of 138 (out of 530) responded (26%).

MenACWY-TT Vaccine Evaluated in Patients With Anatomic/Functional Asplenia

By April 09, 2018

Risk of meningococcal disease up in patients with anatomic/functional asplenia.

Herpes Zoster in Healthy Children Linked to Varicella-Zoster Vaccination

By April 05, 2018

Each of the 7 children received varicella zoster vaccination between 12 and 14 months of age.

Zika Vaccine Could Essentially Eliminate Prenatal Infection

April 03, 2018

The researchers found that for a base-case vaccine efficacy of 75% and vaccination coverage of 90%, immunizing females aged 9 to 49 years would reduce the incidence of prenatal infections by at least 94%, depending on the country-specific Zika attack rate.

Recombinant Influenza Vaccine Found to Be Safe in Children

April 02, 2018

The researchers found that both vaccines were well tolerated in both 6- to 8-year-olds and 9- to 17-year-olds. There were no vaccine-related adverse events in the 6 months of follow-up.

2018 Vaccination Schedule: Adults

April 02, 2018

This schedule indicates the recommended age groups and medical indications for routine administration of currently licensed vaccines for persons 19 years and older.

Children With ASD, Younger Siblings Are Undervaccinated

March 28, 2018

Vaccination rates were significantly lower among younger siblings of children with ASD

2018 Vaccination Schedule: 0-18 Years of Age

March 28, 2018

This schedule indicates the recommended ages for routine administration of currently licensed childhood vaccines for children 0-18 years of age.

Vaccination Schedule: HIV-Infected 0-6 Years of Age

March 27, 2018

Recommended vaccination schedule for HIV-infected children ages 0 to 6 years old.

Vaccine-Derived Protection Against Mumps May Deteriorate

March 22, 2018

The researchers found that vaccine-derived immune protection against mumps waned on average 27 years after vaccination. There was no evidence of heterologous virus genotypes contributing to changes in vaccine effectiveness over time.

Compliance-linked incentives increase infant immunizations rates in rural India

March 14, 2018

Infantile immunization rates were higher among children whose caregivers received compliance-linked incentives when compared to those who received only mobile phone reminders and those who received no intervention.

Impact of Bundled Interventions Examined for Increasing HPV Vaccination Rates

March 14, 2018

The researchers observed an increase in captured opportunities for HPV vaccination, from 46.9 to 63.3%. Centerline shift demonstrated special cause, with 8 consecutive points above the preintervention mean.

2017 Catch-Up Vaccination Schedule: 4 Months-18 Years

March 13, 2018

A catch-up immunization schedule for children 4 months to 18 years of age, including minimum intervals between doses of delayed immunizations.

Maternal Use of TDF Doesn't Further Reduce HBV Transmission

March 08, 2018

Findings in setting with low HBV transmission with administration of hepatitis B immune globulin, vaccine

Does Cumulative Vaccine Exposure in Infants Raise Risk of Certain Infections?

March 07, 2018

The matched odds ratio for estimated cumulative antigen exposure through 23 months was not significant among children with versus those without non-vaccine-targeted infections from 24 through 47 months of age.

Vaccination Outcomes of HPV Primary Care Intervention Examined

March 06, 2018

A greater effect of the intervention was seen for pediatric practices versus family medicine practices and in private practices versus public ones. According to reports from health care professionals, the most used and useful intervention components were communication training and the fact sheets.

Vaccination Coverage Among U.S.- vs. Foreign-Born Adolescents Examined

By March 02, 2018

For hepatitis B (≥3 doses), foreign-born adolescents had significantly lower coverage rates, 89.6% vs. 92.6% for U.S.-born adolescents, even after adjustments were made for demographic and socioeconomic factors.

CDC: Limited Availability of Alternative Yellow Fever Vaccine

By March 01, 2018

As part of the investigational new drug program, only a limited number of clinics can stock Stamaril.