Immunization

Herpes Zoster Recombinant Vaccine Seems Most Effective

November 08, 2018

A network meta-analysis of 5 randomized controlled trials revealed no statistically significant differences between the live attenuated vaccine and placebo for incidence of laboratory-confirmed herpes zoster.

Dengue Vaccine Candidate Gets FDA's Priority Review

By October 31, 2018

Two Phase 3 trials conducted in Asia and Latin America assessed the efficacy of the vaccine in >35,000 individuals aged 2 to 16 years.

Health Officers Express Concerns About Vaccine Exemptions

October 30, 2018

With new California law eliminating nonmedical exemptions, rise in medical exemptions reported

Medical vaccine exemptions increase after elimination of nonmedical exemptions

October 29, 2018

After California eliminated nonmedical exemptions from school-entry vaccinations in 2015, the proportion of kindergarten students who received all required vaccines rose from 92.8% to 95.1%, but the rates of medical exemptions increased 250%.

Does Prior Flu Vaccination Impact Subsequent Vaccine Efficacy in Children?

By October 26, 2018

To better understand the impact of prior-season vaccination on subsequent influenza vaccine effectiveness, researchers conducted a multiseason, test-negative case-control study among vaccinated children 2-17 years old recruited during 3 influenza seasons (2013-2014, 2014-2015, and 2015-2016).

Pneumococcal Vaccine Recs Cause Confusion Among Docs

October 26, 2018

The researchers found that more than 95% of respondents reported routinely assessing adults' vaccination status and recommending both the 13-valent pneumococcal conjugate vaccine (PCV13) and the 23-valent pneumococcal polysaccharide vaccine (PPSV23).

High-Dose Flu Vaccine May Cut Hospitalization in Dialysis Patients

October 24, 2018

The researchers found that by vaccine type, the adjusted rates of first hospitalization were 8.43, 7.88, and 7.99 per 100 patient-months, respectively, and rates for death were 1.00, 0.97, and 1.04, respectively; these differences were not significant.

Afluria, Afluria Quadrivalent Approved for Use in Patients 6 Months and Older

By October 23, 2018

The vaccines are indicated for active immunization against influenza disease caused by virus subtypes A and type B present in the vaccine.

Postnatal Education Increases Pain Relief Use at Vaccinations

October 23, 2018

Based on follow-up data from 2549 participants, the researchers found that utilization of any intervention (breastfeeding, sucrose, or topical anesthetics) was 53.2% for the control group, 61.4% for the pamphlet group, and 63% for the pamphlet and video group.

HPV Vaccination Not Tied to Risky Sexual Behavior in Teen Girls

October 19, 2018

"These findings contribute evidence against any association between HPV vaccination and risky sexual behaviors," the authors write.

Giving Flu Shots in Pharmacies Could Up Vaccination Coverage

October 18, 2018

The researchers found that adding pharmacies with typical business hours averted 11.9 million symptomatic influenza cases, 23,577 to 94,307 deaths, $1.0 billion in direct costs, and $4.2 to 44.4 billion in productivity losses,

Number of Children Not Receiving Vaccines Slightly Increased

October 16, 2018

Although remaining low, the proportion of children who received no vaccine doses by age 24 months increased gradually from 0.9% for children born in 2011 to 1.3% for children born in 2015.

Flu Vaccine Cuts Hospitalization Rates in Pregnant Women

October 15, 2018

Influenza vaccine effectiveness was examined for several countries against laboratory-confirmed influenza-associated hospitalizations during pregnancy.

Gardasil 9 Approved for Use in Women and Men 27 Through 45 Years Old

By October 09, 2018

The approval of the expanded age range was based on data from a clinical trial which evaluated the efficacy of Gardasil (quadrivalent human papillomavirus recombinant vaccine) in 3253 women 27-45 years of age with a median duration of follow-up of 3.5 years post-dose 3.

FDA Approves Accelerated Vaccination Schedule for Ixiaro

By October 05, 2018

Previously, the prescribing information stated that adults should receive the 2 doses 28 days apart.

Influenza Vaccine Dosing Algorithm: 6 Months-8 Years

September 28, 2018

Influenza vaccine dosing algorithm for children 6 months to 8 years of age.

Influenza Vaccine Recommendations: Egg Allergies

September 27, 2018

Influenza vaccine recommendations for individuals who report an allergy to eggs.

Influenza Vaccine Comparisons

September 27, 2018

Compare and contrast influenza vaccines currently available for the 2018-2019 flu season including indicated ages, allergies, and how supplied.

Multivalent Pneumococcal Conjugate Vaccine Gets Breakthrough Tx Designation

By September 20, 2018

The Breakthrough designation follows an FDA examination of results from a Phase 2 randomized, double-blind trial which evaluated the safety and immunogenicity of the treatment in adults aged 60 to 64 years.

Active Choice Intervention Tied to Increase in Flu Shot Rates

September 19, 2018

Compared with control practices over time, the active choice intervention correlated with a significant 9.5% increase in vaccination rates, in adjusted analyses. Similar increases were seen in vaccination rates across times of the day.

AAP Issues Updated Influenza Vaccine Recommendations

By September 06, 2018

According to the Centers for Disease Control and Prevention (CDC), the 2017-2018 flu season was one of the most severe - excluding pandemics - on record.

CDC: HPV Vaccination Rates Increasing Among Adolescents

September 05, 2018

The researchers found that coverage increased for 1 or more dose of HPV vaccine (60.4 to 65.5%), 1 or more dose of meningococcal conjugate vaccine (MenACWY; 82.2 to 85.1%), and 2 or more doses of MenACWY (39.1 to 44.3%) from 2016 to 2017.

Vaccine Storage and Handling

August 30, 2018

Best practices and recommendations for the appropriate storage and handling of vaccines provided by the CDC.

Knowledge of Herd Immunity Can Up Willingness to Be Vaccinated

August 24, 2018

"Education about herd immunity and local vaccination coverage could be a useful tool for increasing willingness to vaccinate, generating benefits both to individuals and communities," the authors write.

CDC: Updated Influenza Vaccination Recommendations for 2018-2019

By August 23, 2018

In general, routine annual vaccination is recommended for all patients ≥6 months of age who have no contraindications.

Catch-Up HPV Doses Effective to Age 21 Against Cervical Neoplasia

August 22, 2018

The strongest protection against CIN2+ was among women who had received at least 3 vaccine doses and had received their first dose at age 14 to 17 years (RR, 0.52) or age 18 to 20 years (RR, 0.65). In women 21 years or older at the time of first dose.

Does Adolescent Vaccination Increase Primary Ovarian Insufficiency Risk?

By August 21, 2018

For this study, researchers investigated the incidence of primary ovarian insufficiency incidence and estimated risk for POI after vaccination with human papillomavirus, Tdap, influenza and meningococcal conjugate using Kaiser Permanente Northwest electronic health records from 2006 to 2014.

Does HPV Legislation Impact Teen Sexual Behaviors?

August 16, 2018

No substantive or significant associations between HPV legislation and adolescent sexual behaviors

Does Prenatal Tdap Vaccination Increase Autism Risk in Offspring?

By August 14, 2018

Currently, the Advisory Committee on Immunization Practices (ACIP) recommends pregnant women receive the Tdap vaccination to prevent pertussis infection.

Flu Vaccine Cuts Mortality in Rheumatoid Arthritis Patients

August 01, 2018

The researchers, after adjusting for potential confounding factors, found that RA patients who received the influenza vaccine had reduced risk of hospitalization for septicemia, bacteremia, or viremia.