Flu Vaccine Cuts Mortality in Rheumatoid Arthritis Patients

August 01, 2018

The researchers, after adjusting for potential confounding factors, found that RA patients who received the influenza vaccine had reduced risk of hospitalization for septicemia, bacteremia, or viremia.

No Higher Risk of Autoimmune Disorders After HPV4 Vaccination

July 30, 2018

No significant risks were seen in exploratory analyses of individual autoimmune disorders, including Bell's palsy, optic neuritis, and Graves' disease.

HPV Vaccine Eliminates Advanced Skin Cancer in 97-Year-Old

July 24, 2018

Doctors tried an unorthodox approach - injecting each tumor with Gardasil, the HPV vaccine. The result: All the tumors completely and rapidly disappeared.

Quadrivalent HPV Vaccine Not Tied to Spontaneous Abortion

July 17, 2018

No evidence of increased risk of spontaneous abortion when inadvertently given before or during pregnancy

Novel Mosaic HIV Vaccine Safe, Immunogenic in Healthy Adults and Monkeys

By July 13, 2018

The regimens were well-tolerated as evident by the comparable incidence of local and systemic reactions among all treatment arms. No grade 4 adverse events or death were reported.

Drop in Childhood Pneumococcal, Hib Deaths From 2000 to 2015

July 12, 2018

The researchers estimated that in HIV-uninfected children aged 1 to 59 months in 2015 there were 294,000 pneumococcal deaths and 29,500 Hib deaths.

Public Health Vaccine Opposition Growing in the United States

July 10, 2018

The authors note that in recent years, a social movement of public health vaccine opposition has been growing in the United States, with an increase in measles outbreaks.

Immunogenicity of Co-Administered Herpes Zoster, Pneumonia Vaccine Assessed

By July 06, 2018

In this Phase 3, open-label, randomized, controlled multicenter study, a total of 865 patients were randomized to receive one of the following vaccine regimens: (1) the first RZV dose and PPSV23 together on Day 0 and the second dose of RZV at Month 2 (N=432); or (2) PPSV23 on Day 0 and then first RZV dose at Month 2 with the second RZV dose at Month 4 (N=433; control group).

Hepatitis B Vaccines Compared in Older Adults With Type 2 Diabetes

By June 26, 2018

For the analysis, study authors looked at data specifically for patients with type 2 diabetes aged 60 to 70 years.

Immunogenicity of Hepatitis A Vaccine Investigated in Older Patients

By June 25, 2018

"All found higher proportions seroprotected (definition varied by study) in younger age groups (ages varied by study) at 15 days post-vaccination but similar seroprotection at 30 days," the study authors reported.

BCG Vaccine Tied to Reduced Hyperglycemia in Type 1 Diabetes

June 22, 2018

Systemic shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis

Parents Say Cancer Prevention Best Reason for HPV Vaccination

June 21, 2018

Findings based on large survey of parents to assess best, worst reasons for vaccination

Varicella Vaccination and Pediatric Arterial Ischemic Stroke: Is There a Link?

By June 20, 2018

The study authors reported that the rate of AIS in the 12 months following vaccination was 7.8 per 100,000 person-years at risk (95% CI: 4.8, 10.9) in patients who received the vaccine versus 6.8 (95% CI: 1.3, 12.2) in those who did not.

HPV Vaccine Under Priority Review for Expanded Age Range

By June 13, 2018

Specifically, the types the vaccine protects against are HPV 16, 18, 31, 33, 45, 52, 58 (which cause ~90% of cervical cancer cases worldwide), and types 6 and 11 which case genital warts.

CDC Issues Updated Advisory Regarding Outbreaks of Hepatitis A

By June 11, 2018

Of the 2500 cases of hepatitis A infection reported between January 2017 and April 2018, 68% were among persons who reported drug use (injection and non-injection), homelessness, or both.

Increase in Requirement for Flu Vaccines at Non-VA Hospitals

June 06, 2018

The researchers found that mandatory influenza vaccination requirements for HCP increased from 37.1% in 2013 to 61.4% in 2017 among all responding hospitals.

No New Adverse Events Reported for DTaP Vaccination

June 04, 2018

The researchers found that 50,157 reports were received by VAERS after DTaP vaccination; 87.7% reported concomitant administration of other vaccines and 11.2% of reports were serious.

CDC: Administration Errors Reported With New Shingles Vaccine

By May 30, 2018

Between October 20, 2017 and February 20, 2018, the Vaccine Adverse Event Reporting System (VAERS) received 155 reports involving RZV, with 13 (8%) involving an administrative error.

Herpes Zoster Vaccination Rates Assessed Among People Living With HIV

By May 28, 2018

The authors found that vaccination rates varied between 1.5% and 42.4% at the 6 institutions assessed and that 21.3% of eligible patients at the University of Colorado received HZV prior to the intervention.

Prevnar 13 Linked to Reduced Risk of CAP Hospitalization in Older Patients

By May 24, 2018

PCV13, marketed as Prevnar 13, was evaluated in a test-negative case-control study in real-world conditions where patients were administered pneumococcal vaccination as advised by their healthcare providers.

HPV Vaccination Coverage, Trends by Age Examined in US

By May 24, 2018

Provider-verified vaccination records obtained from a pilot study conducted in 14-29-year-old patients were utilized to determine the sensitivity and specificity of the self/parent-reported vaccination data.

Need for Gonorrhea Vaccine Highlighted in Light of Global Disease Burden

By May 22, 2018

Dr Vincent also states that target groups should be considered in vaccine development and adds, "It is generally thought that the best target group would be girls and boys aged 9-13, preferably before sexual debut, similar to the HPV vaccination program."

AAP Recommends Shot Over Nasal Spray for 2018-2019 Flu Season

By May 22, 2018

The advisory comes early as physicians are currently placing vaccine orders.

Robust Immune Responses for Herpes Zoster Subunit Vaccine

May 21, 2018

The researchers identified a humoral response in 97.8 and 2% of HZ/su and placebo recipients, respectively, after vaccination.

HPV Vaccination May Offer Protection Against Cervical Precancer

By May 11, 2018

The authors concluded, "There is high-certainty evidence that HPV vaccines protect against cervical precancer in adolescent girls and young women aged 15 to 26," while also indicated that future studies should have long-term follow-up.

Vaccine for Chikungunya Prevention Gets Fast Track Designation

By May 04, 2018

There are currently no approved treatments or vaccines available for chikungunya, a virus transmitted through mosquito bites.

Flu Vaccines Have High Impact, Even With Relatively Low Efficacy

May 01, 2018

The researchers found that even relatively low-efficacy influenza vaccines can have a high impact, especially with optimal distribution across age groups. In order to minimize mortality and DALYs, the optimal distribution of the vaccine uptake shifts toward the elderly as vaccine efficacy declines.

FDA to Review Fluzone Quadrivalent 0.5mL Dose for Younger Patients

By April 27, 2018

The sBLA included clinical data from a Phase 4 study that enrolled nearly 2000 children and assessed the safety and immunogenicity of the 0.5mL dose.

CDC: Recommendations on the Use of Heplisav-B Published

By April 23, 2018

Benefits of protection with 2 doses administered over 1 month make the vaccine an important option for prevention of HBV.

MenB Vaccine Gets Breakthrough Tx Designation for Kids Ages 1 to 9 Years

By April 23, 2018

The Breakthrough designation was based on data from Phase 2 studies which assessed the safety and efficacy of the vaccine in this patient population.