Data from the analysis showed a 73% mean reduction in diarrhea episodes from baseline after treatment with Mytesi for 24 weeks.
Previous Phase 3 studies enrolling >4,500 women (ASPIRE and The Ring Study) have already demonstrated the vaginal ring to be safe and effective in protecting women aged 18-45 years against HIV.
The early-stage clinical trial studied "mosaic" vaccines created to induce immune responses against various HIV subtypes responsible for infections across the world.
A reservoir of virus incorporated in a small proportion of immune cells was observed but no signs of HIV infection were noted in a 9-year-old child who started anti-HIV therapy at 1 month.
This Phase 2b trial assessed HIV-1 viral suppression with rilpivirine (Janssen) and cabotegravir (ViiV Healthcare) given together every 4 or 8 weeks.
In addition to these studies, bictegravir in combination with FTC/TAF is also being evaluated in two ongoing studies involving virologically suppressed adult patients.