FDA Committee Votes on New Oral Testosterone Replacement Tx

By January 11, 2018

The FDA's Bone, Reproductive and Urologic Drugs Advisory Committee (BRUDAC) voted 6 in favor and 13 against the benefit/risk profile of Tlando (testosterone undecanoate) capsules.

Ibuprofen Use Linked to Compensated Hypogonadism in Males

By January 09, 2018

For short term ibuprofen use the effects of compensated hypogonadism are reversible, however the researchers state how it is unknown whether these effects are reversible for long-term ibuprofen use.

AAP Releases New List of 'Choosing Wisely' Recommendations

October 11, 2017

The AAP Section for Endocrinology compiled a list of tests that parents and physicians should question.

Testosterone Replacement Therapy Discontinued

By September 12, 2017

The discontinuation is not due to the safety or efficacy of the drug but due to the the multiple manufacturers that currently provide supply to the U.S. market.

Perrigo Launches Generic Axiron Topical Solution

By July 24, 2017

Endogenous androgens, including testosterone and dihydrotestosterone (DHT), are responsible for the normal growth and development of male sex organs and for the maintenance of secondary sex characteristics.

Testosterone Rx Behaviors Examined at Different Levels of Healthcare

July 24, 2017

"Our results highlight the opportunity to intervene both at the provider and the site level to improve testosterone prescribing," the authors write.

Metabolic Outcomes in Trans Teens Receiving Cross-Sex Hormones

April 12, 2017

The researchers found that of the 72 subjects taking testosterone, at each visit significant increases in hemoglobin/hematocrit levels and BMI were recorded, as was a decrease in high-density lipoprotein level.

Perrigo Approved for Generic Axiron Solution

By March 01, 2017

Perrigo has received final approval from the Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Testosterone Topical Solution, the generic version of Eli Lilly's Axiron Topical Solution.

Testosterone Trials Show Short-Term Benefits but CV Risk Still Unclear

February 22, 2017

While trials show it boosts bone density and lowers anemia risk, heart risks also seen

Testosterone May Protect Against CV Events in Hypogonadal Men

By February 13, 2017

According to a study published in the Journal of Cardiovascular Pharmacology and Therapeutics, long-term testosterone therapy may have protective cardiovascular (CV) effects in men with hypogonadism.

Certain Pain Meds May Have Significant Endocrinologic Effects

By February 10, 2017

Chronic pain patients being treated with certain opioid and non-opioid medications had significantly lower serum concentrations of free testosterone (fTe) and free estradiol (fE2), highlighting the potential endocrinologic side effects of these drugs. These were the findings of a new study published in the journal Drug Testing and Analysis.

Gel-Based Alternative to Traditional Vasectomy in the Works

February 08, 2017

Primate study shows injected gel may one day be alternative to traditional vasectomy

Health Food Store Employees Often Recommend Age-Restricted Supplements to Teens

January 03, 2017

Authors say pediatricians need to discourage their use for athletic performance

Company Hopes to Deliver 'Virtually Painless Treatment Experience' with QuickShot Testosterone

By December 21, 2016

Antares Pharma announced the submission of a New Drug Application (NDA) for QuickShot Testosterone (testosterone enanthate auto-injector) to the Food and Drug Administration (FDA) to treat males with low testosterone associated with hypogonadism.

OPIAD Management Requires a Multidisciplinary Care Team Approach

By December 13, 2016

Despite initial recognition of opioid-induced androgen deficiency (OPIAD) as a possible consequence of opioid use more than four decades ago, few studies have systematically investigated hormonal changes induced by long-term opioid administration.

Erythrocytosis Development Assessed in Men Treated with Implantable Testosterone Pellets

November 21, 2016

Men treated with implantable testosterone pellets have a statistically significant increase in mean hematocrit, but it is unlikely to be clinically relevant, according to research published in The Journal of Urology.

FDA Adds New Warning to All Testosterone Replacement Products

October 25, 2016

Healthcare professionals and patients are encouraged to report any adverse reactions.

Testosterone Solution Safety Tested in 6-Month Trial of Androgen Men

August 22, 2016

Once-daily 2% testosterone solution (T-sol) is safe and effective for sex drive and energy in hypogonadal men, according to a study published online in The Journal of Urology.

Testosterone Therapy May Improve Sexual Function in Older Men

June 30, 2016

Gel hormone treatment led to improved libido, increased sexual activity

Long-Acting Testosterone Improves Sexual Function in Men with T2DM

By May 06, 2016

For males with mild hypogonadism, only scores in sexual desire showed significant improvement

Androxy Available Again for Testosterone Replacement

By April 25, 2016

Upsher-Smith announced that Androxy (fluoxymesterone) tablets are now available.

Can Testosterone Tx Reduce Anemia in Hypogonadal Men?

April 18, 2016

Decreased prevalence of anemia and components of metabolic syndrome after 54 weeks of tx

Does Testosterone Tx Reduce Hospital Readmission in Men with Low Testosterone?

By April 13, 2016

Older men on testosterone therapy were less likely to experience complications requiring hospital readmission within 1 month of discharge than men not using testosterone therapy, according to a study published in Mayo Clinical Proceedings.

Testosterone Therapy May Lower Risk of CV Events in Older Men

By April 05, 2016

Testosterone therapy helped elderly males with low testosterone levels and pre-existing coronary artery disease reduce their risks of major adverse cardiovascular events, including strokes, heart attacks, and death.

FDA: Major Labeling Changes for Opioid Pain Meds

By March 22, 2016

The Food and Drug Administration (FDA) announced it is requiring class-wide safety labeling changes for all immediate-release (IR) opioid pain medicines.

Testosterone Solution 2% Evaluated in Hypogonadal Men

February 22, 2016

Application of once-daily topical testosterone effectively restores normal testosterone levels in men, according to a study published in the March issue of The Journal of Urology.

Testosterone Therapy in Older Men: Benefits and Risks Evaluated in New Study

February 18, 2016

Testosterone treatment may offer moderate benefit in improving sexual function in older men, but further research is needed to establish possible risks, according to research published in the New England Journal of Medicine.

Exposure to Opioids Tied to Lower Testosterone Levels, Study Finds

January 04, 2016

Exposure to opioids is associated with increased likelihood of low testosterone levels, with increased odds as age and number of comorbidities increase, according to a study published in Pain Medicine.

Nasal Testosterone Gel May be Discontinued in 2016

By December 31, 2015

Acerus announced that its agreement with an affiliate of Endo International plc regarding the commercialization of Natesto (testosterone) nasal gel in the U.S. and Mexico will be terminated as of June 30, 2016.

Testosterone Levels Not Linked to Autonomic Neuropathy in T1DM

November 18, 2015

Lower testosterone concentrations at years 10, 17 not linked to cardiovascular autonomic neuropathy