Hypertension

Prenatal Falling Insulin Requirement Linked to Complications

August 16, 2017

The researchers found that FIR ≥15% correlated with an increased risk of the composite primary outcome (odds ratio, 4.38) and preeclampsia (odds ratio, 6.76), and was more common among women with type 1 diabetes (36.6 versus 14.5%)

Marijuana Use May Increase Risk of Death from Hypertension

August 10, 2017

Over 19,569 person-years of follow-up, the adjusted hazard ratios for death from hypertension among marijuana users was 3.42 (95% confidence interval, 1.20 to 9.79).

Angioedema Risk Assessed for Aliskiren vs. Other Antihypertensives

By August 07, 2017

The case-control analysis found no significant difference in the angioedema risk for aliskiren monotherapy and fixed-dose combination compared to BBs with adjusted odds ratio of 0.99 (95% CI, 0.45-2.20) and 1.06 (0.40-2.76), respectively.

FDA Approves CaroSpir, an Oral Suspension Formulation of Spironolactone

By August 07, 2017

CaroSpir, an aldosterone antagonist, works primarily through competitive binding of receptors at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tube.

Publication of Drug Interaction Unlikely to Impact Prescribing Patterns

By August 02, 2017

The findings point to "minimal to no measurable effect" in lowering the concomitant use.

Cardiovascular Disease Correlated to Daily Sodium Intake Threshold

August 01, 2017

ESI >3.7 g/day correlated with strain parameters and e' velocity, while ESI ≤3.7 g/day was not, after adjustment for speckle-tracking analyst, image quality, study site, age, sex, smoking status, alcohol use, daily blocks walked, diuretic use, estimated glomerular filtration rate, left ventricular mass, ejection fraction, and wall motion score index.

Weight Gain During Adulthood Ups Risk of Major Chronic Diseases

July 20, 2017

As little as 11 pounds gained from early to middle adulthood tied to significantly elevated risk

High Rate of Preeclampsia Underscores Need for New Strategies, Study Finds

July 12, 2017

The findings are particularly important because preeclampsia cases rose from 2.4% of pregnancies in 1980 to 3.8% in 2010, the researchers said.

Severe, Monthly Hypertensive Episodes in a Female Patient

By June 26, 2017

The patient was a 32-year-old nulliparous white female who reported a 5-year history of severe hypertension, hypokalemia, and resultant systolic dysfunction.

Genetics Should Play a Bigger Role in Clinical Decision-Making

June 21, 2017

As home genetic testing grows, patients will be bringing their results to physicians for reaction and response. Physicians will need to be proactively prepared.

Common Medications and Substances that May Induce Hypertension

By June 13, 2017

The three major mechanisms by which medications induce hypertension are volume retention, sympathomimetic activation, and direct vasoconstriction.

Efficacy of Traditional Chinese Medicine Examined for CVD Prevention

June 13, 2017

For patients who can't tolerate or afford hypertension medications, the research suggested some herbal alternatives: tiankuijiangya, zhongfujiangya, jiangyabao, and jiangya.

Study Finds 70% of Home BP Monitor Readings Are Inaccurate

By June 07, 2017

The mean differences from the 2-observer auscultation were "acceptable," but when tested on their owners, most of the home devices were inaccurate by ≥5mmHg.

Beta-Blocker Use and Fall Risk Among Elderly: An Analysis

By June 07, 2017

There was no increased fall risk established in patients using selective beta-blockers (HR 0.92, 95% CI 0.83, 1.01). Factors such as lipid solubility and enzyme activity were also determined to not impact fall risk.

Combo vs. One Standard Medication Assessed in HTN Care

June 07, 2017

Researchers found that a combination of 4 medications - each at 1-quarter dose - was nearly twice as effective as 1 drug at the standard dose.

Packaged Foods Now Have Less Salt, But Excessive Consumption Still an Issue

June 06, 2017

The researchers also found that the average salt content in food consumers purchased decreased for all major packaged foods, including 49mg less salt in every 100g of condiments, sauces, dips, and salty snacks.

Reducing SBP Below Recommended Targets May Reduce CVD, Death Risk

June 02, 2017

Reducing SBP to 120 to 124 mm Hg linked to reduced risk of cardiovascular disease, all-cause mortality

Costs Associated with Modifying Antihypertensive Therapy Investigated

By May 31, 2017

Healthcare utilization costs vary significantly between antihypertensive modification strategies.

Polypharmacy Common in Patients Nearing the End of Life

May 22, 2017

Researchers find many still prescribed long-term disease-preventing medications

Teva Launches Generic Benicar, Benicar HCT

By April 27, 2017

Olmesartan Medoxomil is an angiotensin II receptor blocker (ARB). Olmesartan Medoxomil and Hydrochlorothiazide combines an ARB with a thiazide diuretic.

Study Calls Sodium Guidelines Into Question

April 26, 2017

Dietary sodium intake inversely associated with systolic, diastolic blood pressure in long term

USPSTF Issues Statement on Preeclampsia Screening

April 26, 2017

Grade B recommendation suggests substantial net benefit for screening for pre-eclampsia

Azithromycin and Ventricular Arrhythmia: Is There a Link?

April 19, 2017

Individuals who took azithromycin weren't any more likely to develop ventricular arrhythmia than those who took amoxicillin, however, those taking azithromycin were at higher risk than those who didn't take antibiotics.

How Metoprolol Helps Reduce Damage During Heart Attack

By April 18, 2017

The data showed patients treated with metoprolol during acute myocardial infarction had a 40% reduced extent of microvascular obstruction.

Do Uric Acid Lowering Drugs Reduce BP in Hypertensive Patients?

By April 14, 2017

In general, there was low quality evidence from three trials indicating no reduction in systolic (-6.2mmHg, 95% CI: -12.8 to 0.5) or diastolic (-3.9mmHg, 95% CI: -9.2 to 1.4) 24-hour ambulatory BP with uric acid lowering drugs vs. placebo.

Can Gray Hair Predict Risk of Coronary Artery Disease?

By April 10, 2017

Researchers conducted an observational study of 545 adult men.

Endocrine Hypertension Screening Statement Released

By April 07, 2017

The Task Force that authored the Society's statement aimed to review the different forms of endocrine hypertension, focusing on prevalence, clinical presentation, recommendations on when to perform case detection testing, and available case-detection tests.

CDC: Daily Sodium Intake in U.S. Still High

By March 31, 2017

Hypertension, a known risk factor for cardiovascular disease, can be managed by reducing sodium intake to lower blood pressure.

Evaluations of Emergency Medicine Residents Examined for Gender Bias

March 27, 2017

Through all of residency, researchers found that the rate of milestone attainment was 12.7% higher for male residents.