Hypertension

HTN Tx Intensification Common Upon Discharge in US Vets

September 19, 2018

Fourteen percent of patients were discharged with intensified antihypertensive treatment, more than half of whom had well-controlled blood pressure prior to hospital admission.

Hydralazine Linked to Amenorrhea in Premenopausal Patient

By September 18, 2018

This case highlights a possible relationship between the administration of hydralazine and the development of amenorrhea.

Second Impurity Identified in Recalled Valsartan Products

By September 17, 2018

In July, several valsartan medications were recalled due to the detection of N-nitrosodimethylamine, an impurity classified as a probable human carcinogen.

AHA: Resistant Hypertension Diagnosis, Tx Guidelines Updated

September 14, 2018

Ruling out Rx non-compliance, white coat syndrome, and interfering medications necessary

Cancer Risk Associated With Recalled Valsartan Products Examined

September 14, 2018

For single cancer outcomes, risk for colorectal, uterine cancer increased, but not significantly so

Single, Fixed-Dose Combo Pills Improve Hypertension Outcomes

September 12, 2018

Researchers compared clinical outcomes and medication adherence for patients prescribed 1 angiotensin-converting enzyme inhibitor or angiotensin II-receptor blocker plus 1 thiazide diuretic, either as a single-pill FDC or as a multi-pill combination.

Asthma Medicine Recalled Due to Tablet Mix-Up That May Pose Safety Risk

By August 31, 2018

The risk of a mixing-up the treatments is especially high for pregnant women, says the Food and Drug Administration (FDA), as losartan is indicated to treat high blood pressure and could harm or kill a fetus.

Labeling Mix-Up Prompts Recall of HCTZ Bottles That May Contain Another Diuretic

By August 29, 2018

To date, there have been no reports of any adverse events related to this recall.

Triple combo antihypertension Tx improves blood pressure control in hypertension

August 16, 2018

In this randomized controlled trial, patients receiving triple combination antihypertension therapy (TCAT) were more likely to achieve their blood pressure target compared to those with usual care at 6 months.

Case: Hypertensive Crisis Following Use of Armodafinil + MAOI

By August 15, 2018

This case involved a 36-year-old female with bipolar disorder who presented to the emergency department (ED) with blurry vision, neck stiffness and the "worst headache of (her) life" after taking armodafinil with tranylcypromine.

Labetalol Use Up for Patients With Preeclampsia and Asthma

August 15, 2018

The researchers found that patients with asthma used carboprost less frequently than patients with no asthma (11.4 vs 18.0%) compared with intravenous labetalol, which was used more often among patients with a diagnosis of asthma than those without (18.5 vs 16.7%).

Triple Combo Blood Pressure Pill Can Improve BP Control

August 15, 2018

The researchers found that the proportion of patients achieving target BP was increased with the triple combination pill versus usual care at 6 months (70 vs 55%; risk difference, 12.7%).

Kapspargo Sprinkle Available to Treat Hypertension, Angina, Heart Failure

By August 07, 2018

For patients unable to swallow an intact capsule, the pellets can be sprinkled over soft food (eg, applesauce, yogurt, pudding) or given via a nasogastric (NG) tube.

Use of BP-Interfering Medications Examined Among Patients With Hypertension

By August 02, 2018

To better understand the real-world use of these agents among patients with hypertension, researchers conducted a retrospective drug utilization study using medical and prescription claims from the Marketscan database (January 2008 to December 2014).

Tool Improves Identification of Undiagnosed Hypertension

July 30, 2018

The tool was applied using medical billing data alone and in combination with clinical data from 8.92 million patients from 25 organizations participating in the American Medical Group Association national learning collaborative to calculate and compare predicted and observed adult hypertension prevalence.

Use of 2017 ACC/AHA Guidelines Would Increase HTN Prevalence

July 27, 2018

The researchers found that adoption of the 2017 ACC/AHA hypertension guidelines in the United States would label 70.1 million people (63%) aged 45 to 75 years with hypertension.

Modifiable Midlife Risk Factors Linked to Late-Onset Epilepsy

July 25, 2018

"Although stroke and dementia were both associated with late-onset epilepsy, vascular and lifestyle risk factors were significant even in the absence of stroke or dementia," the authors write.

Heart Meds Recalled After Discovery of Possible Carcinogenic Impurity

By July 16, 2018

As valsartan is used to treat various cardiovascular conditions including heart failure and hypertension, patients should continue to take their medications until they have a replacement product,

More Youth Classified With HTN Using New 2017 AAP Guidelines

July 13, 2018

The researchers found that there was a decrease in the prevalence of hypertension during this time, using both the new guidelines (from 7.7 to 4.2%) and former guidelines (from 3.2 to 1.5%).

Calcium Channel Blocker May Benefit Patients With Type 1 Diabetes

By July 10, 2018

For this study, researchers conducted a randomized, double-blind, placebo-controlled Phase 2 trial (N=24) to assess the efficacy and safety of adding oral verapamil for 12 months to a standard insulin regimen in adults with recent-onset type 1 diabetes (age range: 18 to 45 years).

Hydralazine-Induced Hepatotoxicity Described in Case Report

By July 09, 2018

Symptoms in patients with short latency include fever, rash, and eosinophilia.

Blister Packs for Several Meds Recalled Due to Risk of Harm to Children

By July 09, 2018

The recall affects approximately 470,000 units that include drugs packaged with 3 to 10 tablets per blister card. The blister packs were developed for use in hospitals, however some were sent to retail pharmacies and were likely dispensed for in-home use.

Increase in Prevalence of Pediatric Hypertension With New Definitions

July 06, 2018

Incorporation of new pediatric definitions increased prevalence of hypertension in high-risk youth

Genetic Risk, Lifestyle Predict CVD, Diabetes Independently

June 28, 2018

A total of 339,003 unrelated individuals of white British descent with available genotype and matching genetic data from the UK Biobank cohort study were included in the study.

Should Physicians Treat Family and Friends? Three Experts Weigh In

By June 19, 2018

Although all of the guidelines acknowledge that there are emergent situations in which providing care for a family member or friend is not only permissible but also essential, other situations are frowned upon.

Exposure to Maternal HTN May Up Risk of ASD, ADHD in Child

June 13, 2018

The researchers found that 11 of 20 studies that reported estimates for ASD (777,518 participants) found higher odds with HDP (adjusted odds ratio [aOR], 1.35) in pooled analysis. For the 6 studies reporting adjusted estimates of ADHD (1,395,605 participants), the pooled adjusted OR was 1.29.

Some Evidence Mobile Health Interventions Can Lower CVD Risk

June 08, 2018

mHealth programs generally improve overall cardiovascular disease risk, at least in the short term

Revised Equation May Improve Accuracy of Cardiovascular Disease Risk Estimates

By June 06, 2018

Multiple studies have indicated that the 2013 PCEs - published by the American College of Cardiology/American Heart Association Task Force on Practice Guidelines - substantially misestimated CVD risk.

Improved calculations suggest major changes to statin, aspirin, and blood pressure Tx

June 06, 2018

Updated risk calculations suggest that fewer people should be classified within the high-risk category for CVD.

Consensi Approved to Treat Hypertension and Osteoarthritis Pain

By June 01, 2018

Consensi combines amlodipine besylate, a calcium-channel blocker (CCB), and celecoxib, a nonsteroidal anti-inflammatory drug (NSAID).