Hypertension

Tekturna Oral Pellets Approved to Treat Hypertension in Adults and Children

By November 20, 2017

Tekturna is indicated for the treatment of hypertension in adults and children 6 years of age and older, to lower blood pressure.

Methamphetamine Heart Failure May Present New Phenotype

November 15, 2017

"Clinicians are seeing more heart failure with meth use, suggesting heart failure due to methamphetamine use could be a new epidemic," said lead author, Marin Nishimura, MD, in a statement.

AHA/ACC: New Guidelines Redefine 'High Blood Pressure'

November 14, 2017

In 2013 the U.S. government asked the AHA and ACC to draft new guidelines for blood pressure management.

Routine Hypertension Monitoring May Be Necessary With Some Antipsychotics

By November 10, 2017

Antipsychotics used to treat disorders such as schizophrenia, bipolar disorder, and other psychoses mainly involve D2 receptor antagonism and some newer agents target D4 antagonism.

Prexxartan Oral Solution Gets Tentative FDA Approval

By November 01, 2017

The FDA's final approval is pending the period of patent and/or exclusivity protection, and may not be made effective until the period has expired.

How a Preference for Spicy Foods May Lower Blood Pressure

November 01, 2017

Spicy food enjoyment enhanced sensitivity to salt and reduced salt preference. Salt intake and salt preference were correlated with the regional metabolic activity in the insula and orbitofrontal cortex (OFC).

FDA-Approved Spironolactone Oral Suspension Now Available

By October 30, 2017

First FDA-approved oral liquid dosage form of the potassium-sparing diuretic spironolactone.

Better Risk Factor Modification Strategies Needed for Optimal Stroke Prevention

October 12, 2017

Increases in prevalence of hypertension, diabetes, dyslipidemia, smoking, and drug abuse in AIS

Sauna Bathing May Have Blood Pressure Benefits

By September 29, 2017

Compared to those who reported taking 1 sauna per week - using Cox regression analysis that adjusted for age, smoking, body mass index, and systolic blood pressure - the hazard ratio for incident hypertension in those reporting 2-3 and 4-7 sauna sessions was 0.76 (95% CI; 0.57 - 1.02) and 0.54 (95% CI; 0.32-0.91), respectively.

Post-Op Outcomes for Individualized vs. Standard Blood Pressure Tx

September 27, 2017

The researchers found that the primary outcome event occurred in 38.1 and 51.7% of patients assigned to the individualized treatment group and standard treatment strategy group, respectively.

Increased Med Use Over Time Seen in Older Patients of All BMI Classes

By September 22, 2017

Researchers aimed to determine whether the rise in prescription drug use over time varied by age and obesity status.

Multicomponent Intervention Evaluated as Uncontrolled HTN Treatment

September 20, 2017

The researchers found that from baseline to 18 months, there was a decrease of 19.3 and 12.7 mmHg in the intervention and usual-care groups, respectively.

Effects of Statin Use as Primary Prevention Examined in Older Males

September 18, 2017

The researchers found that over the study period statin use was associated with an 18% lower risk of all-cause mortality and non-significantly lower risk of CVD events and stroke.

Airplane Medical Emergencies: Is it a Physician's Duty to Help?

September 13, 2017

In the United States, Canada, and United Kingdom, physicians do not have the legal duty to assist unless there is a prior patient-physician relationship.

Intensive Blood Pressure Control Linked to Increased CKD Risk

September 08, 2017

However, cardiovascular events, all-cause mortality risk decrease with intensive blood pressure lowering

Hypertension Awareness, Tx and Control Significantly Lagging in Young Men

August 30, 2017

The investigators also found that young people with hypertension were much more likely to be obese. Seventy-three percent fell in the obesity category compared to 57% of middle-aged people with hypertension and 42% of older people with hypertension.

CDC: Heart Disease, Hearing Loss Screening Overlooked for Many Newborns

August 29, 2017

"Newborn screening at birth is crucial to quickly identify infants at risk of hearing loss and congenital heart disease so they can receive early intervention and follow-up care," Brenda Fitzgerald, MD, director of the CDC.

Increases in BP, Hypertension Incidence Linked to Certain NSAIDs

By August 28, 2017

The PRECISION-ABPM study included 444 patients (408 with osteoarthritis; 36 RA) who had evidence of, or were at increased risk for, coronary artery disease.

Communicative Techniques Identified to Improve HTN Rx Adherence

August 24, 2017

Patients were 3 times less likely to take their medications if their providers didn't use a more collaborative style, such as asking open-ended questions, and ensuring they understood instructions, the investigators found.

High Systolic BP Linked to Negative Cognitive Outcomes

August 23, 2017

Researchers find that healthy reductions may benefit blacks even more than whites

AAP: Updated Pediatric Hypertension Guidelines Published

August 22, 2017

Other changes to the guidelines include a more limited recommendation to check blood pressure measurements only at preventive care visits, a streamlined evaluation and management of abnormal readings, revised recommendations on when to perform echocardiography, and a revised definition of left ventricular hypertrophy.

Antihypertensive Tx Analyzed in Younger, Predominantly Healthy Adults

By August 17, 2017

"Antihypertensive drugs have a small absolute effect to reduce cardiovascular mortality and morbidity primarily due to reduction in cerebrovascular mortality and morbidity," write the authors.

Prenatal Falling Insulin Requirement Linked to Complications

August 16, 2017

The researchers found that FIR ≥15% correlated with an increased risk of the composite primary outcome (odds ratio, 4.38) and preeclampsia (odds ratio, 6.76), and was more common among women with type 1 diabetes (36.6 versus 14.5%)

Marijuana Use May Increase Risk of Death from Hypertension

August 10, 2017

Over 19,569 person-years of follow-up, the adjusted hazard ratios for death from hypertension among marijuana users was 3.42 (95% confidence interval, 1.20 to 9.79).

Angioedema Risk Assessed for Aliskiren vs. Other Antihypertensives

By August 07, 2017

The case-control analysis found no significant difference in the angioedema risk for aliskiren monotherapy and fixed-dose combination compared to BBs with adjusted odds ratio of 0.99 (95% CI, 0.45-2.20) and 1.06 (0.40-2.76), respectively.

FDA Approves CaroSpir, an Oral Suspension Formulation of Spironolactone

By August 07, 2017

CaroSpir, an aldosterone antagonist, works primarily through competitive binding of receptors at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tube.

Publication of Drug Interaction Unlikely to Impact Prescribing Patterns

By August 02, 2017

The findings point to "minimal to no measurable effect" in lowering the concomitant use.

Cardiovascular Disease Correlated to Daily Sodium Intake Threshold

August 01, 2017

ESI >3.7 g/day correlated with strain parameters and e' velocity, while ESI ≤3.7 g/day was not, after adjustment for speckle-tracking analyst, image quality, study site, age, sex, smoking status, alcohol use, daily blocks walked, diuretic use, estimated glomerular filtration rate, left ventricular mass, ejection fraction, and wall motion score index.

Weight Gain During Adulthood Ups Risk of Major Chronic Diseases

July 20, 2017

As little as 11 pounds gained from early to middle adulthood tied to significantly elevated risk

High Rate of Preeclampsia Underscores Need for New Strategies, Study Finds

July 12, 2017

The findings are particularly important because preeclampsia cases rose from 2.4% of pregnancies in 1980 to 3.8% in 2010, the researchers said.