HYPERRAB S/D Rx

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HYPERRAB S/D

Vaccines
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Generic Name and Formulations:

Rabies immune globulin (human) 150 IU/mL; soln for IM inj; preservative-free; latex-free.

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Indications for HYPERRAB S/D:

Postexposure prophylaxis of rabies.

Adult:

See literature. Give by IM inj preferably at the time of 1st vaccine dose; may be given through 7th day after 1st vaccine dose is given. 20 IU/kg (0.133mL/kg) once. If feasible, up to full dose should be infiltrated in area around wound and the rest into deltoid muscle of upper arm or lateral thigh muscle.

Children:

Not recommended.

Warnings/Precautions:

Previously immunized with rabies vaccine with a confirmed adequate rabies antibody titer: not recommended. Contains human plasma; monitor for possible infection transmission. IgA-deficiency. Thrombocytopenia or other bleeding disorders. Prior history of allergic reactions to human immunoglobulins. Have epinephrine inj available. Pregnancy (Cat.C).

Interactions:

Avoid live vaccines within 3 months.

Pharmacological Class:

Immune globulin.

Adverse Reactions:

Inj site reactions, mild temp elevations; rare: angioneurotic edema, rash, nephrotic syndrome, anaphylactic shock.

How Supplied:

Single-use vial (2mL, 10mL)—1