HUMULIN R U-500

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Generic Name for HUMULIN R U-500

Regular insulin (human, recombinant) 500Units/mL; inj; contains m-cresol.

Legal Classification:

Rx

Manufacturer of HUMULIN R U-500

Lilly, Eli and Company

Indications for HUMULIN R U-500

Diabetes.

Adults and Children:

SC injection only. Onset approx 30 minutes, peak 1.75–4hrs, duration up to 24 hrs.

Also:

Precautions for HUMULIN R U-500

Instruct patients on diet, exercise, blood or urine testing, proper administration of insulin, change in species of origin, type or purity of insulin, and management of hypoglycemia. Dosage increase may be required during infection, illness, stress, trauma, and pregnancy. Dosage decrease may be needed with renal or hepatic dysfunction.

Interactions for HUMULIN R U-500

Potentiated by salicylates, MAOIs, alcohol, sulfa drugs, some ACE inhibitors, drugs that inhibit pancreatic function (eg, octreotide). Antagonized by corticosteroids, isoniazid, niacin, thiazides, phenothiazines, sympathomimetics. Variable effects with β-blockers, clonidine, lithium salts, alcohol. Onset may be delayed if regular insulin is mixed with zinc insulin. Regular and NPH insulins may be mixed and used immediately or stored for future use.

Adverse Reactions for HUMULIN R U-500

Hypoglycemia, hypokalemia, local or systemic allergy, lipodystrophy, edema.

How is HUMULIN R U-500 supplied?

Vials 70/30, 50/50, N, R (U-100)—10mL
R (U-500)—20mL
Prefilled disposable Pen (70/30, N)—5x3mL

Related Disease:

Diabetes mellitus~hyperglycemic agents

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