Hormone Replacement Therapies
| HORMONE REPLACEMENT THERAPIES | ||||
|---|---|---|---|---|
| Brand | Generic | Form | Strength | Dosing Frequency |
| ORAL ESTROGEN | ||||
| CENESTIN | Synthetic conj. estrogens, A | tabs | 0.3mg, 0.45mg, 0.625mg, 0.9mg, 1.25mg | Once daily |
| ENJUVIA | Synthetic conj. estrogens, B | tabs | 0.3mg, 0.45mg, 0.625mg, 0.9mg, 1.25mg | Once daily |
| ESTRACE | Estradiol (micronized) | tabs | 0.5mg, 1mg, 2mg | Once daily |
| FEMTRACE | Estradiol | tabs | 0.9mg, 1.8mg | Once daily |
| MENEST | Esterified estrogens | tabs | 0.3mg, 0.625mg, 1.25mg, 2.5mg | Once daily |
| OGEN | Estropipate* | tabs | 0.625mg, 1.25mg, 2.5mg | Once daily |
| ORTHO-EST | Estropipate* | tabs | 0.625mg, 1.25mg | Once daily |
| PREMARIN | Conj. estrogens | tabs | 0.3mg, 0.45mg, 0.625mg, 0.9mg, 1.25mg, 2.5mg | Once daily |
| TRANSDERMAL ESTROGEN | ||||
| ALORA | Estradiol | matrix patch | 0.025, 0.05, 0.075, 0.1mg/day | Twice weekly |
| CLIMARA | Estradiol | matrix patch | 0.025, 0.0375, 0.05, 0.06, 0.075, 0.1mg/day | Once weekly |
| DIVIGEL | Estradiol | topical gel | 0.25, 0.5, 1mg/pkt | Once daily |
| ELESTRIN | Estradiol | topical gel | 0.87g/pump | Once daily |
| ESTRADERM | Estradiol | reservoir patch | 0.05, 0.1mg/day | Twice weekly |
| ESTRASORB | Estradiol | topical emulsion | 1.74g/pouch | 2 pouches once daily |
| ESTROGEL | Estradiol | topical gel | 1.25g/pump | 1 pump once daily |
| EVAMIST | Estradiol | topical spray | 1.53mg/spray | Initially 1 spray daily; may increase to 2–3 sprays if needed |
| MENOSTAR | Estradiol | matrix patch | 0.014mg/day | Once weekly |
| MINIVELLE | Estradiol | patch | 0.0375, 0.05, 0.075, 0.1mg/day | Twice weekly |
| VIVELLE | Estradiol | matrix patch | 0.05, 0.1mg/day | Twice weekly |
| VIVELLE-DOT | Estradiol | matrix patch | 0.025, 0.0375, 0.05, 0.075, 0.1mg/day | Twice weekly |
| VAGINAL ESTROGEN | ||||
| ESTRING | Estradiol | ring | 7.5mcg/24hrs | Once every 90 days |
| FEMRING | Estradiol | ring | 0.05mg/day, 0.1mg/day | Once every 3mos |
| PREMARIN | Conj. estrogens | cream | 0.625mg/g | Daily |
| VAGIFEM | Estradiol | vaginal tabs | 10mcg | Once daily for 2wks, then twice weekly |
| ORAL PROGESTOGEN | ||||
| AYGESTIN | Norethindrone acetate | tabs | 5mg | Once daily |
| PROMETRIUM | Progesterone (micronized) | caps | 100mg, 200mg, 300mg | Once daily |
| PROVERA | MPA | tabs | 2.5mg, 5mg, 10mg | Once daily |
| ORAL ESTROGEN + PROGESTOGEN | ||||
| ACTIVELLA | Estradiol + norethindrone acetate | tabs | 0.5mg + 0.1mg; 1mg + 0.5mg | Once daily |
| ANGELIQ | Estradiol + drospirenone | tabs | 0.5mg + 0.25mg; 1mg + 0.5mg | Once daily |
| FEMHRT | Norethindrone acetate + ethinyl estradiol | tabs | 0.5mg + 2.5mcg
1mg + 5mcg |
Once daily, continuously Note: Progestin listed first |
| PREFEST | Estradiol (3 tabs); then estradiol + norgestimate (3 tabs) | tabs | 1mg; then 1mg + 0.09mg | Once daily, sequentially |
| PREMPHASE | Conj. estrogens (14 tabs); then conj. estrogens + MPA (14 tabs) | tabs | 0.625mg; then 0.625mg + 5mg | Once daily, sequentially |
| PREMPRO | Conj. estrogens + MPA (28 tabs) | tabs | 0.3mg + 1.5mg, 0.45mg + 1.5mg,
0.625mg + 2.5mg, 0.625mg + 5mg |
Once daily, continuously |
| TRANSDERMAL ESTROGEN + PROGESTOGEN | ||||
| CLIMARA PRO | Estradiol + levonorgestrel | matrix patch | 0.045mg + 0.015mg/day | Once weekly |
| COMBIPATCH | Estradiol + norethindrone acetate | matrix patch | 0.05mg + 0.14mg/day
0.05mg + 0.25mg/day |
Twice weekly |
| NOTES | ||||
|
Not an inclusive list of medications and/or official indications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling. Estrogen component is listed first for combination products. Listed strengths are not necessarily the same as the dosage. Listed dosing frequency is for use in HRT; may be other frequencies for other uses. Some products are given cyclically. *Formerly piperazine estrone sulfate. Tablet strengths given as mg sodium estrone sulfate. Matrix patch: Estradiol is embedded in the adhesive layer that is applied directly to the skin. Reservoir patch: Estradiol is contained in a drug reservoir and its release is controlled by a copolymer membrane; contains more layers than matrix patch. MPA = medroxyprogesterone acetate. (Rev. 5/2013) |
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