Hepatitis B Dosing
| HEPATITIS B DOSING* | ||
|---|---|---|
| Brand | Generic | Usual Dosage |
| Baraclude | entecavir | Adults: ≥16yrs: Take on empty stomach. Compensated liver disease:
nucleoside-naïve: 0.5mg once daily; lamivudine-refractory or known lamivudine or telbivudine resistance
mutations: 1mg once daily. Decompensated liver disease: 1mg once daily.
Children: <16yrs: Not recommended. |
| Epivir-HBV | lamivudine | Adults: 100mg once daily.
Children: 2–17yrs: 3mg/kg (max 100mg) once daily; <2yrs: Not recommended. |
| Hepsera | adefovir | Adults and Children ≥12yrs: 10mg once daily. |
| Intron A | interferon alfa-2b | Adults: 5million IU daily or 10million IU IM or SC three times weekly for 16 wks.
Children: ≥1yr: 3million IU/m² SC three times weekly for 1 week, then increase to 6million IU/m² (max 10million IU) 3 times weekly for a total of 16–24 wks; <1yr: Not recommended. |
| Pegasys | peginterferon alfa-2a | Adults: ≥18yrs: 180mcg SC once weekly for 48 wks.
Children: <18yrs: Not recommended. |
| Tyzeka | telbivudine | Adults: ≥16yrs: 600mg once daily.
Children: <16yrs: Not recommended. |
| Viread | tenofovir | Adults and Children ≥12yrs (≥35kg): 300mg once daily. |
| NOTES | ||
|
*For Hepatitis B Adult Renal Dosing Chart or full prescribing information, refer to individual drug monographs found at www.empr.com. (Rev. 2/2013) |
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