GONITRO Rx

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GONITRO

Angina
Only 4 drugs may be compared at once

Generic Name and Formulations:

Nitroglycerin 400mcg; per pkt; sublingual powder.

Select therapeutic use:

Indications for GONITRO:

Acute relief of angina attack. Acute prophylaxis of angina pectoris.

Adult:

Treatment: 1 or 2 packets (400mcg/packet) sublingually at onset, may give 1 additional packet every 5 mins as needed; max 3 packets in 15 mins. Prophylaxis: 5–10 mins before activity.

Children:

Not established.

Contraindications:

Concomitant PDE-5 inhibitors (eg, avanafil, sildenafil, tadalafil, vardenafil), soluble guanylate cyclase stimulators (eg, riociguat). Severe anemia. Increased intracranial pressure. Acute circulatory failure or shock.

Warnings/Precautions:

Hypotensive (constrictive pericarditis, aortic or mitral stenosis) or volume depleted. Hypertrophic obstructive cardiomyopathy. Use lowest effective dose. Elderly. Pregnancy. Nursing mothers.

Interactions:

See Contraindications. Hypotension potentiated by PDE-5 inhibitors, riociguat, antihypertensives, beta-adrenergic blockers, calcium channel blockers. Potentiated by high-dose aspirin. May antagonize tissue-type plasminogen activators (t-PA). Avoid ergotamine and related drugs; monitor if unavoidable.

Pharmacological Class:

Nitrate.

Adverse Reactions:

Headache, dizziness, paresthesia, hypotension.

Generic Availability:

NO

How Supplied:

Pwd pkts—12, 36, 96