Glaucoma

Roclatan Meets Primary Endpoint in Phase 3 Glaucoma Study

By May 24, 2017

The evaluation of Roclatan has been ongoing in two distinct trials.

FDA Accepts NDA for Glaucoma Drug Rhopressa

By May 15, 2017

The FDA has completed its initial 60-day review of the New Drug Application (NDA) for Rhopressa (netarsudil; Aerie) 0.02% and determined that it's sufficiently complete to permit a substantive review.

NDA Re-Submitted for Novel Glaucoma Drug

By February 27, 2017

Valeant have re-submitted their NDA for latanoprostene bunod ophthalmic solution after receiving a Complete Response Letter from the FDA last summer.

IOP Management in Glaucoma Affected by Certain Systemic Medications

January 13, 2017

Systemic -blocker use linked to lower IOP; ACEI, ARB, statin, sulfonylurea linked to higher IOP

Glaucoma Management: 6 Things PCPs Need to Know

December 27, 2016

Should be aware of the scope and symptoms, medication and side effects, and surgical options

First Case of Zika-Related Glaucoma in Infant ID'd

December 01, 2016

Brazilian baby developed condition after being exposed to virus in womb

FDA Approves XEN Glaucoma Treatment System

November 22, 2016

Allergan announced that the Food and Drug Administration (FDA) has approved the Xen Glaucoma Treatment System for the management of refractory glaucomas, including cases where previous surgical treatment has failed.

Promising Results for Fixed-Dose Combination Eye Drop for Glaucoma

By September 16, 2016

Aerie Pharmaceuticals announced topline data from the Mercury 1 study, a Phase 3 trial evaluating the fixed-dose combination product, Roclatan (netarsudil/latanoprost ophthalmic solution) 0.02%/0.005%, to lower intraocular pressure (IOP) in patients with glaucoma.

NDA for Novel Glaucoma, Ocular Hypertension Drug Submitted to FDA

By September 08, 2016

Aerie announced the submission of its New Drug Application (NDA) to the Food and Drug Administration (FDA) for Rhopressa (netarsudil ophthalmic solution) 0.02% to lower intraocular pressure (IOP) in patients with glaucoma or ocular hypertension.

Promise for Drug-Eluting Contact Lenses to Treat Glaucoma

August 31, 2016

Latanoprost-eluting contact lenses are effective at lowering intraocular pressure in a glaucoma model, according to an experimental study published online August 29 in Ophthalmology.

Bottle Design Could Impact Dosing for Glaucoma Patients

By August 24, 2016

A statistically significant variability in the force needed to squeeze a drop from common glaucoma medications was observed in a study published in the Journal of Glaucoma.

Ahmed Glaucoma Valve Implant Outcomes Improve With Antifibrotic Use

August 10, 2016

Mitomycin C (MMC) and 5-flurouracil (5-FU) improve outcomes following Ahmed glaucoma valve (AGV) implantation, according to a study published online August 4 in Clinical & Experimental Ophthalmology.

Combigan Ophthalmic Solution Available in New Size

By June 02, 2016

Combigan (brimonidine tartrate, timolol maleate; Allergan) ophthalmic solution is now available in a new 15mL bottle size for a 90-day supply.

Antidepressant Linked to Increased IOP in Glaucoma Patient

May 09, 2016

In a case report published online April 30 in Clinical & Experimental Ophthalmology, venlafaxine-induced increase in intraocular pressure (IOP) is described in a patient with open angle glaucoma.

Study Suggests These Drugs Are Best for Reducing IOP in Glaucoma

April 19, 2016

Highest-ranking class for reducing intraocular pressure was prostaglandins for 1999, 2004, 2009

Laser-Assisted Cataract Sx With Femtosecond Shows no Added Benefits

March 17, 2016

For patients undergoing toric intraocular lens insertion, visual outcomes are similar for femtosecond laser-assisted cataract surgery (LCS) and phacoemulsification cataract surgery (PCS), according to research published online in Clinical & Experimental Ophthalmology.

Bevacizumab, Triamcinolone Improve Outcomes in Patients Undergoing Cataract Surgery

March 09, 2016

Both linked to improvements in visual acuity; only triamcinolone tied to sustained improvement in CMT

Leafy Vegetable Diet can Lower Primary Open-Angle Glaucoma Risk

January 15, 2016

Higher dietary nitrate and green leafy vegetable intake is associated with reduced risk of primary open-angle glaucoma (POAG), according to a study published online in JAMA Ophthalmology.

Intraocular Pressure Increase is Tied to Yoga Positions

January 13, 2016

For individuals with and without open-angle glaucoma, intraocular pressure (IOP) increases shortly after starting yoga exercises with head-down positions, according to a study published online in PLOS ONE.

Three New Glaucoma-Related Genes Found by Researchers

January 12, 2016

Three newly identified genes associated with primary open angle glaucoma bring the total number of such genes to 15, according to a study published online January 11 in Nature Genetics.

Patient Age at Initial Cataract Surgery Varies by Location

December 30, 2015

Five-fold variation for highest versus lowest age-standardized cataract surgery rate

Patient Factors ID'd for Intention to Use Marijuana for Glaucoma

December 28, 2015

Factors include perceptions of legality of marijuana use, satisfaction with current glaucoma care

Prostaglandin Analogs Impact Circadian IOP-Related Patterns

December 09, 2015

For patients with glaucoma, prostaglandin analogs seem to affect circadian intraocular pressure (IOP)-related patterns, according to a study published in the December issue of Clinical & Experimental Ophthalmology.

Statin Treatment Linked to Reduced Risk of Cataracts

December 07, 2015

Simvastatin plus ezetimibe linked to lower risk of cataract development versus placebo

Training Module Helps Optometrists ID Glaucoma

October 13, 2015

Particularly with inclusion of additional examination techniques

Glaucoma Tx Candidate Non-Inferior in Phase 3 Study

By September 17, 2015

Aerie Pharmaceuticals announced that the Phase 3 trial, Rocket 2, for Rhopressa achieved its primary efficacy endpoint demonstrating non-inferiority to timolol for the treatment of increased intraocular pressure (IOP) in patients with glaucoma or ocular hypertension.

Body Levels of Trace Metals Linked to Odds of Glaucoma

August 07, 2015

Blood manganese and mercury levels are negatively and positively associated with glaucoma, respectively.

Reduction in Glaucoma Risk With Metformin Appears Dose-Dependent

May 29, 2015

Metformin is associated with a lower risk of developing open-angle glaucoma (OAG), according to a study published in JAMA Ophthalmology.

Agomelatine Cuts Ocular Pressure With Glaucoma

April 10, 2015

Agomelatine, a melatonin agonist, decreases pressure in stable, consistent way

Study: Equivalent Glaucoma Grading Seen by Specialty Optometrists

April 01, 2015

Community optometrists have moderate inter-observer agreement for grading limbal anterior chamber depth (LACD), while equivalent agreement is seen for specialist optometrists and ophthalmologists, according to a new study.