Glaucoma
| GLAUCOMA◊ | |||||
|---|---|---|---|---|---|
| Brand & Company | Generic | Strength | Size | Formulation† | Adult Dosing Regimen |
| α2-AGONISTS | |||||
| ALPHAGAN P
(Allergan) |
brimonidine tartrate | 0.1%, 0.15% | 5mL, 10mL, 15mL | soln** | 1 drop every 8 hours. |
| IOPIDINE
(Alcon) |
apraclonidine (as HCl) | 0.5% | 5mL, 10mL | soln* | 1–2 drops 3 times daily. |
| COMBINATION α2-AGONIST + β-BLOCKER | |||||
| COMBIGAN
(Allergan) |
brimonidine tartrate | 0.2% | 5mL, 10mL, 15mL | soln* | 1 drop every 12 hours. |
| timolol (as maleate) | 0.5% | ||||
| β-BLOCKERS | |||||
| BETAGAN
(Allergan) |
levobunolol HCl | 0.5% | 5mL, 15mL | soln* | 1–2 drops once or twice daily. |
| BETIMOL
(Vistakon) |
timolol (as hemihydrate) | 0.25%, 0.5% | 5mL, 10mL, 15mL | soln* | 1 drop twice daily. |
| BETOPTIC S
(Alcon) |
betaxolol HCl | 0.25% | 2.5mL, 5mL, 10mL, 15mL | susp* | 1–2 drops twice daily. |
| —
(Sandoz) |
betaxolol HCl | 0.5% | 5mL, 10mL, 15mL | soln* | 1–2 drops twice daily. |
| —
(Sandoz) |
carteolol HCl | 1% | 5mL, 10mL, 15mL | soln* | 1 drop twice daily. |
| ISTALOL
(ISTA) |
timolol (as maleate) | 0.5% | 5mL | soln* | 1 drop once daily in the morning. |
| OPTIPRANOLOL
(Bausch & Lomb) |
metipranolol HCl | 0.3% | 5mL, 10mL | soln* | 1 drop twice daily. |
| TIMOPTIC
(Aton Pharma) |
timolol (as maleate) | 0.25%, 0.5% | 5mL, 10mL, 15mL | soln* | Initially 1 drop of 0.25% twice daily; max 1 drop of 0.5% twice daily. |
| TIMOPTIC OCUDOSE
(Aton Pharma) |
0.25%, 0.5% | 60 | soln | ||
| TIMOPTIC-XE
(Aton Pharma) |
0.25%, 0.5% | 2.5mL, 5mL | gel-forming soln | 1 drop once daily. | |
| CARBONIC ANHYDRASE INHIBITORS | |||||
| AZOPT
(Alcon) |
brinzolamide | 1% | 2.5mL, 5mL, 10mL, 15mL | susp* | 1 drop 3 times daily. |
| DIAMOX SEQUELS
(Teva) |
acetazolamide | 500mg | 100 | sust-rel caps | 500mg twice daily. |
| NEPTAZANE
(Fera) |
methazolamide | 25mg
50mg |
90 | tabs | 50–100mg twice to three times daily. |
| TRUSOPT
(Merck) |
dorzolamide HCl | 2% | 10mL | soln* | 1 drop 3 times daily. |
| COMBINATION CARBONIC ANHYDRASE INHIBITOR + β-BLOCKER | |||||
| COSOPT
(Merck) |
dorzolamide HCl | 2% | 10mL | soln* | 1 drop twice daily. |
| timolol maleate | 0.5% | ||||
| COSOPT PF
(Merck) |
2% | 0.2mL | soln**** | ||
| 0.5% | |||||
| CHOLINERGIC (MIOTIC) AGONISTS | |||||
| ISOPTO CARBACHOL
(Alcon) |
carbachol | 1.5% | 15mL | soln* | 2 drops up to 3 times daily. |
| 3% | 15mL, 30mL | ||||
| ISOPTO CARPINE
(Alcon) |
pilocarpine HCl | 1%, 2%, 4% | 15mL | soln* | 2 drops up to 3–4 times daily or more if needed. Heavily pigmented irides: need higher concentrations. |
| PILOPINE HS
(Alcon) |
pilocarpine HCl | 4% | 4gm | gel* | Apply ½ inch ribbon in lower conjunctival sac at bedtime. |
| CHOLINESTERASE INHIBITORS | |||||
| PHOSPHOLINE IODIDE
(Pfizer) |
ecothiophate iodide | 0.03%, 0.06%, 0.125%, 0.25% | 5mL | soln | 0.03% soln instilled twice daily.
If being transferred due to unsatisfactory control with pilocarpine, carbachol, epinephrine, etc, use higher strength soln. |
| PROSTAGLANDIN ANALOGS | |||||
| LUMIGAN
(Allergan) |
bimatoprost | 0.01%, 0.03% | 2.5mL, 5mL, 7.5mL | soln* | 1 drop once daily in the evening. |
| TRAVATAN Z
(Alcon) |
travoprost | 0.004% | 2.5mL, 5mL | soln*** | 1 drop once daily in the evening. |
| XALATAN
(Pfizer) |
latanoprost | 0.005% | 2.5mL | soln* | 1 drop once daily in the evening. |
| ZIOPTAN
(Merck) |
tafluprost | 0.0015% | 0.3mL | soln**** | 1 drop once daily in the evening. |
| PROSTANOIDS (DOCOSANOIDS) | |||||
| RESCULA
(Novartis) |
unoprostone isopropyl | 0.15% | 5mL | soln* | 1 drop twice daily. |
| SYMPATHOMIMETICS | |||||
| PROPINE
(Allergan) |
dipivefrin HCl | 0.1% | 5mL, 10mL, 15mL | soln* | 1 drop every 12 hrs. |
| NOTES | |||||
|
† soln = solution; sust-rel caps = sustained release capsules; susp = suspension; tabs = tablets * Contains benzalkonium chloride. May be absorbed by soft contact lenses. ** Contains purite. *** Contains sofZia (boric acid, propylene glycol, sorbitol, zinc chloride). **** Preservative-free. ◊ Not an inclusive list. Please see drug monograph or www.eMPR.com (Rev. 1/2013) |
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