Geriatrics

Lithium, Divalproex Efficacy Examined in Older Bipolar Patients

By August 09, 2017

Results demonstrated that lithium was more effective in controlling manic signs and symptoms, as defined by a change from baseline Young Mania Rating Scale.

Does Aspirin Protect Against Symptoms of Depression?

By August 08, 2017

Research on whether aspirin (which has both anti-inflammatory and anti-atherosclerotic properties) has an impact on depression has been limited.

Parkinsonism Treatments

July 28, 2017

Parkinson's drug treatment chart categorized by pharmacological class.

Neuropathic Pain Treatments

July 27, 2017

Chart with medications used to treat neuropathic pain, including diabetic peripheral neuropathy, fibromyalgia, and postherpetic neuralgia.

Recombinant Flu Vaccine May Protect Seniors Better than Traditional Vaccine

By June 22, 2017

Flublok Quadrivalent, approved by the Food and Drug Administration (FDA) in October 2016, is a recombinant protein-based vaccine developed without the use of eggs.

Do PPIs Increase the Risk of Dementia?

By June 22, 2017

The data indicated continuous PPI use was tied to a reduced risk of cognitive function decline vs. never use (hazard ratio [HR] 0.78, 95% CI: 0.66-0.93; P=0.005).

NAMS: New Position Statement on Hormone Therapy

By June 20, 2017

Firstly, NAMS reiterates that HT should be individualized for each patient and requires periodic reevaluation for risks and benefits of selected therapy.

FDA Fast Tracks Drug for Hallucinations Disorder in Lewy Body Dementia

By June 19, 2017

Nelotanserin is a novel once-daily oral 5HT2A inverse agonist. The 5HT2A receptor has been associated with neuropsychiatric effects, including visual hallucinations.

Potential Microbial Growth Prompts Recall of Several Injectable Solutions

By June 16, 2017

The affected lots were distributed in the U.S, Dutch Antilles, Barbados, Canada, Philippines, Kuwait, and Singapore between January to June 2017.

PPIs May Benefit Older Patients on Antiplatelet Therapy

June 15, 2017

Research suggests proton-pump inhibitors should be co-prescribed in patients age 75 years

Beta-Blocker Use and Fall Risk Among Elderly: An Analysis

By June 07, 2017

There was no increased fall risk established in patients using selective beta-blockers (HR 0.92, 95% CI 0.83, 1.01). Factors such as lipid solubility and enzyme activity were also determined to not impact fall risk.

"UTI" Diagnosis May Lead to Harmful Antibiotic Overtreatment

By June 05, 2017

In their paper, the authors noted that "healthy urinary tracts host a ubiquitous, complex microbial community" and that the presence of these microorganisms are often beneficial to overall well-being.

Inhaled L-dopa Meets Endpoints in Parkinson's Disease Study

By June 05, 2017

The study's primary endpoint was meaningful improvement in motor function as defined by the Unified Parkinson's Disease Rating Scale—Part III.

Caloric Restriction May Slow Biological Aging

May 25, 2017

Study found middle-aged adults who reduced their intake showed slower biological aging

Polypharmacy Common in Patients Nearing the End of Life

May 22, 2017

Researchers find many still prescribed long-term disease-preventing medications

Medicaid Standards of Care Rule Gets Pushed Back

May 18, 2017

The standards were set by a rule adopted in 2014 in an effort to improve the quality of care that disabled individuals receive outside of institutions.

Major Gaps in Life Expectancy Across the U.S.

May 09, 2017

Socioeconomic and race/ethnicity factors explain 60% of the variation in life expectancy, the researchers found, while quality and availability of health care accounts for 27% of the life expectancy gap.

Hip Fracture Risk Up in New Users of Sleep Aids

May 03, 2017

New users of sleep aids have fracture rate 2.5 times greater than peers not taking these drugs

Osteoporosis Treatments

May 02, 2017

Osteoporosis treatment and prevention doses including recommended calcium and vitamin D supplemental doses.

Major Bleeding Risk Similar with Antiplatelets, OAs in Elderly AF Patients

April 17, 2017

Elderly taking aspirin, clopidogrel have major bleeding similar to that seen with oral anticoagulants

2017 Vaccination Schedule: Adults

April 13, 2017

This schedule indicates the recommended age groups and medical indications for routine administration of currently licensed vaccines for persons 19 years and older.

Tolerability, Adherence to Alzheimer's Drugs Assessed

By April 11, 2017

Overall, the researchers found no variation in tolerability or adherence to the 3 medications based on gender, race, education or age.

Benzodiazepine Use Among Alzheimer's Patients May Up Pneumonia Risk

By April 10, 2017

Analysis found that the use of benzodiazepines was significantly associated with an increased risk of pneumonia (aHR 1.28, 95% CI: 1.07-1.54) but not for the similarly acting non-benzodiazepines (aHR 1.10, 95% CI: 0.84-1.44).

Intracranial Bleed Risk Compared for Apixaban, Warfarin in A-fib Patients

By March 29, 2017

Patients taking apixaban showed significantly less intracranial hemorrhage (0.33% per year) vs. patients taking warfarin (0.80% per year) no matter the type and location.

Concerns Raised Over Commonly Prescribed OAB Drug

March 28, 2017

Among elderly patients, oxybutynin was frequently prescribed and continued; incidence, 27.3%; prevalence, 33.2%.

How Often is Orthostatic Hypotension a Risk Factor in Incident Falls?

March 21, 2017

The researchers observed an increased relative risk of UF with impaired orthostatic BP stabilization at 40 seconds after standing (OH[40]) (relative risk, 1.52).

Initiative May Reduce Hospitalizations of Nursing Home Residents

March 21, 2017

The researchers estimated net reductions of 2.2 to 9.3% in the probability of an all-cause hospitalization and 1.4 to 7.2% in the probability of a potentially avoidable hospitalization for participating facility residents

Does Statin Use Increase Diabetes Risk in Elderly Women?

By March 15, 2017

A 10-year follow-up period found that statin exposure was associated with a higher risk of treatment for new-onset diabetes.

Novel Approaches to Hearing Loss Needed as Rates Set to Double in U.S.

March 06, 2017

According to the researchers of a new letter published in JAMA, in 2020, 55.4% of all adults with hearing loss will be 70 or older. In 2060, that rate will jump to 67.4%.