ADD THIS DRUG TO MY LIST

Select the drug indication to add to your list

GABITRIL
Seizure disorders
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:

GABITRIL Rx

Generic Name and Formulations:
Tiagabine HCl 2mg, 4mg, 12mg, 16mg; tabs.

Company:
Cephalon, Inc.

e-Prescribe this drug via Surescripts


Therapeutic Use:

Indications for GABITRIL:

Adjunct in partial seizures.

Adult Dose for GABITRIL:

Take with food. Use lower doses and titrate slower if not on concomitant enzyme-inducing drug(s). 12–18yrs: 4mg once daily for 1 week; may increase to 8mg/day in 2 divided doses for 1 week; then may increase by 4–8mg weekly to clinical response or up to 32mg/day in 2–4 divided doses. ≥18yrs: 4mg once daily for 1 week; may increase by 4–8mg weekly to clinical response or up to 56mg/day in 2–4 divided doses.

Children's Dose for GABITRIL:

Not recommended.

Pharmacological Class:

GABA reuptake inhibitor.

Warnings/Precautions:

Hepatic impairment: reduce dose. Reduce dose or discontinue if generalized weakness occurs. Adjust dose if spike and wave discharges on EEG with cognitive or neuropsychiatric events occur. Suicidal tendencies (monitor). Avoid abrupt cessation. Elderly. Pregnancy (Cat.C). Nursing mothers.

Interactions:

CNS depression potentiated by alcohol, triazolam, other CNS depressants. Tiagabine levels reduced by enzyme inducers (eg, phenytoin, carbamazepine, primidone, phenobarbital). May interact with valproate (monitor). May affect or be affected by highly protein bound drugs.

Adverse Reactions:

Dizziness, asthenia, somnolence, fatigue, GI upset/pain, nervousness, tremor, abdominal pain, concentration difficulties, dysphasia, confusion, other CNS effects, serious rash; possible long-term ophthalmologic effects.

Generic Availability:

YES

How Supplied:

Tabs—100

Sign Up for Free e-newsletters