FLAGYL Rx

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FLAGYL

Bacterial infections
Protozoal infections
Vaginal infections
Only 4 drugs may be compared at once

Generic Name and Formulations:

Metronidazole 250mg, 500mg; scored tabs.

Company:

Pfizer Inc.

Select therapeutic use:

Indications for FLAGYL:

Susceptible anaerobic infections, including intraabdominal, skin and skin structures, gynecologic, bacterial septicemia, bone and joint, CNS, lower respiratory tract, endocarditis.

Adult:

Parenteral form usually used first. 7.5mg/kg every 6 hours for 7–10 days; max 4g/day.

Children:

Not recommended.

Contraindications:

Pregnancy (1st trimester for trichomoniasis).

Warnings/Precautions:

CNS disease. Discontinue if neurological symptoms occur. Severe hepatic disease: reduce dose. Candidiasis. History of blood dyscrasias. Monitor leukocytes before and after therapy. Elderly: monitor serum levels. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:

Avoid alcohol during and for 3 days after use. Do not give within 2 weeks of disulfiram (possible psychotic reactions). May potentiate oral anticoagulants, phenytoin, lithium. Antagonized by phenobarbital, phenytoin, other hepatic enzyme inducers. May impair phenytoin clearance. Potentiated by cimetidine, other hepatic enzyme inhibitors. Interferes with serum chemistry tests.

See Also:

FLAGYL 375

FLAGYL I.V. INJECTION

Pharmacological Class:

Nitroimidazole.

Adverse Reactions:

Seizures, peripheral neuropathy, GI upset, anorexia, constipation, headache, metallic taste, ECT changes, dysuria.

How Supplied:

Tabs—50, 100; Caps 375mg—50; IV—24

FLAGYL 250mg tablets (Qty:21)

appx. price $177.00

Indications for FLAGYL:

Amebic dysentery. Amebic liver abscess.

Adult:

Dysentery: 750mg. Abscess: 500–750mg. Both: 3 times daily for 5–10 days.

Children:

35–50mg/kg/day in 3 divided doses for 10 days.

Contraindications:

Pregnancy (1st trimester for trichomoniasis).

Warnings/Precautions:

CNS disease. Discontinue if neurologic symptoms occur. Severe hepatic disease: reduce dose. History of blood dyscrasias. Candidiasis. Monitor leukocytes before and after therapy. Elderly: monitor serum levels. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:

Avoid alcohol during and for 3 days after use. Do not give within 2 weeks of disulfiram (possible psychotic reactions). May potentiate oral anticoagulants, phenytoin, lithium. Antagonized by phenobarbital, phenytoin, other hepatic enzyme inducers. May impair phenytoin clearance. Potentiated by cimetidine, other hepatic enzyme inhibitors. Interferes with serum chemistry tests.

See Also:

FLAGYL 375

Pharmacological Class:

Nitroimidazole.

Adverse Reactions:

Seizures, peripheral neuropathy, GI upset, anorexia, constipation, headache, metallic taste, ECT changes, dysuria.

How Supplied:

Tabs—50, 100; Caps 375mg—50

FLAGYL 250mg tablets (Qty:21)

appx. price $177.00

Indications for FLAGYL:

Trichomoniasis.

Adult:

250mg 3 times daily for 1 wk. Or, if patient is not pregnant, 2g in 1–2 divided doses on same day. Before repeating course, reconfirm diagnosis and allow 4–6 wks between courses. Treat consorts also.

Children:

Not recommended.

Contraindications:

Pregnancy (1st trimester for trichomoniasis).

Warnings/Precautions:

CNS disease. Discontinue if neurological symptoms occur. Severe hepatic disease: reduce dose. History of blood dyscrasias. Monitor leukocytes before and after therapy. Elderly: monitor serum levels. Pregnancy (Cat.B, 2nd and 3rd trimesters). Nursing mothers: not recommended.

Interactions:

Avoid alcohol during and for 3 days after use. Do not give within 2 weeks of disulfiram (possible psychotic reactions). May potentiate oral anticoagulants, phenytoin, lithium. Antagonized by phenobarbital, phenytoin, other hepatic enzyme inducers. May impair phenytoin clearance. Potentiated by cimetidine, other hepatic enzyme inhibitors. Interferes with serum chemistry tests.

See Also:

FLAGYL 375

FLAGYL ER

Pharmacological Class:

Antiprotozoal/antibacterial.

Adverse Reactions:

GI upset, headache, metallic taste, dysuria, cystitis, incontinence, Candida overgrowth, seizures, peripheral neuropathy, ECT changes; neutropenia, pancreatitis (rare).

How Supplied:

Tabs—50, 100; ER—30; Caps 375mg—50

FLAGYL 250mg tablets (Qty:21)

appx. price $177.00