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FIORICET
Migraine and headache
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Drug Name:

FIORICET Rx

Generic Name and Formulations:
Butalbital 50mg, acetaminophen 300mg, caffeine 40mg; caps.

Company:
Actavis

Therapeutic Use:

Indications for FIORICET:

Tension (or muscle contraction) headache.

Adult:

1–2 caps every 4hrs; max 6/day.

Children:

Not recommended.

See Also:

FIORICET w. CODEINE

Pharmacological Class:

Barbiturate + analgesic.

Contraindications:

Porphyria. Also with Codeine: post-op pain management in children who have undergone tonsillectomy and/or adenoidectomy.

Warnings/Precautions:

Hepatotoxicity (acetaminophen >4g/day). Drug abusers. Impaired hepatic or renal function (monitor). Acute abdominal conditions. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended. Also with Codeine: risk of respiratory depression and death related to ultra-rapid metabolizers of codeine (esp. in children in post-op tonsillectomy and/or adenoidectomy). Obstructive sleep apnea. Head injury. Increased intracranial pressure. Hypothyroidism. Addison’s disease. GI or GU obstruction. Abuse potential. Labor and delivery.

Interactions:

May be potentiated by MAOIs. May potentiate alcohol, general anesthetics, tranquilizers, sedative-hypnotics, other narcotic analgesics or CNS depressants. Induction of drug-metabolizing hepatic enzymes. Acetaminophen may cause false (+) urine test for 5-hydroxyindoleacetic acid. Codeine may increase serum amylase levels.

Adverse Reactions:

Drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, intoxicated feeling, depression, confusion, paradoxical excitement; rare: serious skin reactions (eg, Stevens-Johnson syndrome, toxic epidermal necrolysis); discontinue if occurs; overdosage: respiratory depression, hepatotoxicity.

How Supplied:

Caps—100

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