Select therapeutic use:
Indications for FIORICET:
Tension (or muscle contraction) headache.
1–2 caps every 4hrs; max 6/day.
Porphyria. Also with Codeine: post-op pain management in children who have undergone tonsillectomy and/or adenoidectomy.
Hepatotoxicity (acetaminophen >4g/day). Drug abusers. Impaired hepatic or renal function (monitor). Acute abdominal conditions. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended. Also with Codeine: risk of respiratory depression and death related to ultra-rapid metabolizers of codeine (esp. in children in post-op tonsillectomy and/or adenoidectomy). Obstructive sleep apnea. Head injury. Increased intracranial pressure. Hypothyroidism. Addison’s disease. GI or GU obstruction. Abuse potential. Labor and delivery.
May be potentiated by MAOIs. May potentiate alcohol, general anesthetics, tranquilizers, sedative-hypnotics, other narcotic analgesics or CNS depressants. Induction of drug-metabolizing hepatic enzymes. Acetaminophen may cause false (+) urine test for 5-hydroxyindoleacetic acid. Codeine may increase serum amylase levels.
Barbiturate + analgesic.
Drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, intoxicated feeling, depression, confusion, paradoxical excitement; rare: serious skin reactions (eg, Stevens-Johnson syndrome, toxic epidermal necrolysis); discontinue if occurs; overdosage: respiratory depression, hepatotoxicity.