Select therapeutic use:
Indications for FEXMID:
Acute muscle spasms, as an adjunct to rest and physical therapy.
≥15yrs: initially 5mg 3 times daily, may increase to 7.5mg or 10mg 3 times daily; max 2–3 weeks. Elderly or hepatic impairment: consider less frequent dosing.
<15yrs: not recommended.
During or within 14 days of MAOIs. Acute post-MI. Arrhythmias, heart block, other conduction disturbances. CHF. Hyperthyroidism.
Hepatic impairment (if moderate to severe: not recommended). Urinary retention. Angle-closure glaucoma. Increased intraocular pressure. Elderly. Pregnancy (Cat.B). Nursing mothers.
See Contraindications. Hypertensive crisis with MAOIs. Potentiates anticholinergics, alcohol, other CNS depressants. May antagonize guanethidine, clonidine. Tramadol increases seizure risk.
Muscle relaxant (central).
Drowsiness, dry mouth, dizziness, fatigue, headache, GI upset, irritability, nervousness, asthenia, blurred vision, confusion.