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Breast cancer
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Generic Name and Formulations:

Letrozole 2.5mg; tabs.

Select therapeutic use:

Indications for FEMARA:

In postmenopausal women: Adjuvant treatment of hormone receptor positive early breast cancer; Extended adjuvant treatment of early breast cancer after 5 years of adjuvant tamoxifen therapy; First-line treatment of hormone receptor positive or unknown, locally advanced or metastatic breast cancer; Treatment of advanced breast cancer with disease progression following antiestrogen therapy.


2.5mg once daily. Continue until tumor progression is evident. Adjuvant or extended adjuvant therapy: treat for at least 24 months (see literature). Severe hepatic impairment or cirrhosis: 2.5mg every other day.


Not applicable.


Women of premenopausal endocrine status. Pregnancy (Cat.X).


Severe renal or hepatic impairment. Monitor bone mineral density, serum cholesterol. Nursing mothers.

Pharmacological Class:

Aromatase inhibitor.

Adverse Reactions:

Pain (bone, musculoskeletal, and others), hot flashes, arthralgia, flushing, asthenia, edema, headache, dizziness, hypercholesterolemia, sweating increased, GI upset, fatigue, dyspnea, cough, insomnia, hypertension, alopecia, anorexia, weight changes, hypercalcemia, pleural effusion, vertigo; thromboembolic or cardio- or cerebrovascular events (rare).

How Supplied:


FEMARA 2.5mg tablets (Qty:30)

appx. price $725.00