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FASLODEX
Breast cancer
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Drug Name:

FASLODEX Rx

Generic Name and Formulations:
Fulvestrant 50mg/mL; soln for IM inj.

Company:
AstraZeneca Pharmaceuticals

Therapeutic Use:

Indications for FASLODEX:

Hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following antiestrogen therapy.

Adult:

Give by IM inj slowly (1–2 mins/injection). 500mg (as two 5mL injections, one in each buttock) on days 1, 15, 29, then once per month thereafter. Moderate hepatic impairment: 250mg (as one 5mL injection) on days 1, 15, 29, then once per month thereafter.

Children:

Not applicable.

Pharmacological Class:

Estrogen receptor antagonist.

Warnings/Precautions:

Bleeding diatheses, thrombocytopenia, or anticoagulant use. Moderate to severe hepatic impairment. Pregnancy (Cat.D; avoid); exclude pregnancy before starting. Nursing mothers: not recommended.

Adverse Reactions:

Inj site pain, GI upset, bone pain, arthralgia, headache, back pain, fatigue, pain in extremity, hot flash, anorexia, asthenia, musculoskeletal pain, cough, dyspnea, constipation; increased hepatic enzymes, hypersensitivity reactions.

Metabolism:

Hepatic (CYP3A4); 99% protein bound.

Elimination:

Fecal (primarily), renal.

How Supplied:

Prefilled syringe kit (2 x 5mL)—1

FASLODEX

  • 50mg tablets (Qty:30)
  • appx. price $545.00
GoodRx

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