EXTRA STRENGTH BAYER PLUS OTC

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EXTRA STRENGTH BAYER PLUS

Arthritis/rheumatic disorders
Nonnarcotic analgesics
Only 4 drugs may be compared at once

Generic Name and Formulations:

Aspirin 500mg; buffered with calcium carbonate; caplets.

Select therapeutic use:

Indications for EXTRA STRENGTH BAYER PLUS:

Arthritic and rheumatic conditions.

Adult:

Rheumatoid arthritis, arthritis and pleurisy of SLE: initially 3g daily in divided doses; target plasma salicylate level 150–300mcg/mL. Osteoarthritis: up to 3g/day in divided doses. Spondyloarthropathies: up to 4g/day in divided doses.

Children:

JRA: initially 90–130mg/kg per day in divided doses; target plasma salicylate level 150–300mcg/mL.

Contraindications:

NSAID allergy. Viral infection in children and teenagers. 3rd trimester pregnancy.

Warnings/Precautions:

History of asthma or peptic ulcer. Severe hepatic or renal dysfunction. Bleeding disorders. Diabetes. Gout. Pregnancy, nursing mothers: not recommended.

Interactions:

Potentiates anticoagulants, hypoglycemics, methotrexate, acetazolamide, valproic acid, highly protein-bound drugs. Urinary alkalinizers, antacids, corticosteroids may increase excretion. May antagonize ACE inhibitors, β-blockers, diuretics, uricosurics. Increased bleeding risk with NSAIDs or chronic, heavy alcohol use. NSAIDs increase risk of renal dysfunction.

See Also:

BAYER

EXTRA STRENGTH BAYER

Pharmacological Class:

Salicylate.

Adverse Reactions:

GI upset/bleed, prolonged bleeding time, anaphylaxis, salicylism.

How Supplied:

Ext Str tabs, caplets, Plus—50; Ext Str gelcaps—40, 80; Bayer Tabs—12, 24, 50, 100, 200, 300, 365; Caplets—50, 100, 200

Indications for EXTRA STRENGTH BAYER PLUS:

Pain. Fever.

Adult:

500mg–1g every 4–6hrs; usual max 4g daily.

Children:

Use chewable tabs.

Contraindications:

NSAID allergy. Viral infection in children and teenagers. 3rd trimester pregnancy.

Warnings/Precautions:

History of asthma or peptic ulcer. Severe hepatic or renal dysfunction. Bleeding disorders. Diabetes. Gout. Pregnancy, nursing mothers: not recommended.

Interactions:

Potentiates anticoagulants, hypoglycemics, methotrexate, acetazolamide, valproic acid, highly protein-bound drugs. Urinary alkalinizers, antacids, corticosteroids may increase excretion. May antagonize ACE inhibitors, β-blockers, diuretics, uricosurics. Increased bleeding risk with NSAIDs or chronic, heavy alcohol use. NSAIDs increase risk of renal dysfunction.

See Also:

BAYER

EXTRA STRENGTH BAYER

BAYER CHEWABLE

Pharmacological Class:

Salicylate.

Adverse Reactions:

GI upset/bleed, prolonged bleeding time, anaphylaxis, salicylism.

How Supplied:

Tabs—12, 24, 50, 100, 200, 300, 365; Caplets—50, 100, 200; Gelcaps—40, 80; Ext Str tabs, caplets, Plus—50; Ext Str Gelcaps—40, 80; Children's—36