Generic Name and Formulations:
Aspirin 500mg; buffered with calcium carbonate; caplets.
Company:
Bayer Corp, Consumer Care Div.
Arthritic and rheumatic conditions.
Rheumatoid arthritis, arthritis and pleurisy of SLE: initially 3g daily in divided doses; target plasma salicylate level 150–300micrograms/mL. Osteoarthritis: up to 3g/day in divided doses. Spondyloarthropathies: up to 4g/day in divided doses.
JRA: initially 90–130mg/kg per day in divided doses; target plasma salicylate level 150–300micrograms/mL.
BAYER ARTHRITIS PAIN REGIMEN, EXT STR
Salicylate.
NSAID allergy. Viral infection in children and teenagers. 3rd trimester pregnancy.
History of asthma or peptic ulcer. Severe hepatic or renal dysfunction. Bleeding disorders. Diabetes. Gout. Pregnancy, nursing mothers: not recommended.
Potentiates anticoagulants, hypoglycemics, methotrexate, acetazolamide, valproic acid, highly protein-bound drugs. Urinary alkalinizers, antacids, corticosteroids may increase excretion. May antagonize ACE inhibitors, β-blockers, diuretics, uricosurics. Increased bleeding risk with NSAIDs or chronic, heavy alcohol use. NSAIDs increase risk of renal dysfunction.
GI upset/bleed, prolonged bleeding time, anaphylaxis, salicylism.
Ext Str Arthritis Reg—50; Ext Str tabs, caplets, Plus—50; Ext Str gelcaps—40, 80; Bayer Tabs—12, 24, 50, 100, 200, 300, 365; Caplets—50, 100, 200
Pain. Fever.
500mg–1g every 4–6 hours; usual max 4g daily.
Use chewable tabs.
Salicylate.
NSAID allergy. Viral infection in children and teenagers. 3rd trimester pregnancy.
History of asthma or peptic ulcer. Severe hepatic or renal dysfunction. Bleeding disorders. Diabetes. Gout. Pregnancy, nursing mothers: not recommended.
Potentiates anticoagulants, hypoglycemics, methotrexate, acetazolamide, valproic acid, highly protein-bound drugs. Urinary alkalinizers, antacids, corticosteroids may increase excretion. May antagonize ACE inhibitors, β-blockers, diuretics, uricosurics. Increased bleeding risk with NSAIDs or chronic, heavy alcohol use. NSAIDs increase risk of renal dysfunction.
GI upset/bleed, prolonged bleeding time, anaphylaxis, salicylism.
Tabs—12, 24, 50, 100, 200, 300, 365; Caplets—50, 100, 200; Gelcaps—40, 80; Ext Str tabs, caplets, Plus—50; Ext Str Gelcaps—40, 80; Children's—36