EXCEDRIN EXTRA STRENGTH OTC

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EXCEDRIN EXTRA STRENGTH

Nonnarcotic analgesics
Only 4 drugs may be compared at once

Generic Name and Formulations:

Acetaminophen 250mg, aspirin 250mg, caffeine 65mg; caplets.

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Indications for EXCEDRIN EXTRA STRENGTH:

Minor aches and pains.

Adult:

Take with full glass of water. 2 caplets every 6 hours as needed; max 8 caplets/day.

Children:

Not recommended.

Contraindications:

NSAID allergy. Varicella, vaccinia in children and teenagers. 3rd trimester of pregnancy.

Warnings/Precautions:

Reye's syndrome. Persistent or unresponsive headache. Hypertension. Cardiovascular disease. Asthma. Peptic ulcer. GI bleeding disorders. Liver cirrhosis. Hepatic or renal impairment. Discontinue if signs/symptoms of GI bleed, tinnitus, loss of hearing, or new symptoms occur. Reevaluate if pain worsens or persists for >10 days or if fever worsens or persists for >3 days. Elderly (≥60yrs). Pregnancy. Nursing mothers.

Interactions:

May potentiate anticoagulants, hypoglycemics, methotrexate. May antagonize uricosurics. Increased risk of liver toxicity and/or GI bleed with ≥3 alcoholic drinks/day or concomitant other drugs containing acetaminophen, NSAIDs. Caution with diuretics, corticosteroids.

Pharmacological Class:

Analgesic + salicylate.

Adverse Reactions:

Gastric upset, prolonged bleeding time, urticaria, anaphylaxis; overdosage: salicylism, hepatoxicity.

How Supplied:

Caplets—24, 200