Generic Name and Formulations:
Etodolac 400mg, 500mg.
Company:
Various generic manufacturers
Osteoarthritis. Rheumatoid arthritis.
Initially 600mg–1g/day in 2–3 divided doses; usual max 1g/day in divided doses; may increase to 1.2g/day when needed.
Not recommended.
NSAID (pyranocarboxylic acid deriv.).
Aspirin allergy. Late pregnancy. Coronary artery bypass graft surgery.
Discontinue if signs/symptoms of liver disease develop. History of upper GI disease. Asthma. Renal or hepatic impairment. Advanced kidney disease: not recommended. Heart failure. Hypertension. Edema. Bleeding disorders. Monitor blood, hepatic, renal, and ocular function in chronic use. Dehydrated. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.
Antacids reduce serum levels. Avoid salicylates, phenylbutazone. Monitor anticoagulants, cyclosporine, lithium, digoxin, methotrexate. Renal toxicity may be potentiated with diuretics. May antagonize ACE inhibitors.
Dyspepsia, GI upset, edema, asthenia/malaise, dizziness, dysuria, urinary frequency, depression, nervousness, renal or hepatic toxicity, rash (discontinue if occurs), pruritus, chills/fever, GI bleed, peptic ulcer. See literature re: risk of cardiovascular events.
Formerly known under the brand names Lodine (caps, tabs); Lodine XL (ext-rel tabs).
Contact supplier.
Pain.
Initially 200mg–400mg every 6–8 hrs as needed; usual max 1g/day in divided doses; may increase to 1.2g/day when needed.
Not recommended.
NSAID (pyranocarboxylic acid deriv.).
Aspirin allergy. Late pregnancy. Coronary artery bypass graft surgery.
Discontinue if signs/symptoms of liver disease develop. History of upper GI disease. Asthma. Renal or hepatic impairment. Advanced kidney disease: not recommended. Heart failure. Hypertension. Edema. Bleeding disorders. Monitor blood, hepatic, renal, and ocular function in chronic use. Dehydrated. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.
Antacids reduce serum levels. Avoid salicylates, phenylbutazone. Monitor anticoagulants, cyclosporine, lithium, digoxin, methotrexate. Renal toxicity may be potentiated with diuretics. May antagonize ACE inhibitors.
Dyspepsia, GI upset, edema, asthenia/malaise, dizziness, dysuria, urinary frequency, depression, nervousness, renal or hepatic toxicity, rash (discontinue if occurs), pruritus, chills/fever, GI bleed, peptic ulcer. See literature re: risk of cardiovascular events.
Formerly known under the brand name Lodine.
Contact supplier.