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Etodolac Tablets
Arthritis/rheumatic disorders
Nonnarcotic analgesics
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Drug Name:

Etodolac Tablets Rx

Generic Name and Formulations:
Etodolac 400mg, 500mg.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Etodolac Tablets:

Osteoarthritis. Rheumatoid arthritis.

Adult:

Initially 600mg–1g/day in 2–3 divided doses; usual max 1g/day in divided doses; may increase to 1.2g/day when needed.

Children:

Not recommended.

See Also:

Etodolac ext-rel Tablets

Etodolac Capsules

Contraindications:

Aspirin allergy. Late pregnancy. Coronary artery bypass graft surgery.

Warnings/Precautions:

Discontinue if signs/symptoms of liver disease develop. History of upper GI disease. Asthma. Renal or hepatic impairment. Advanced kidney disease: not recommended. Heart failure. Hypertension. Edema. Bleeding disorders. Monitor blood, hepatic, renal, and ocular function in chronic use. Dehydrated. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Antacids reduce serum levels. Avoid salicylates, phenylbutazone. Monitor anticoagulants, cyclosporine, lithium, digoxin, methotrexate. Renal toxicity may be potentiated with diuretics. May antagonize ACE inhibitors.

Adverse Reactions:

Dyspepsia, GI upset, edema, asthenia/malaise, dizziness, dysuria, urinary frequency, depression, nervousness, renal or hepatic toxicity, rash (discontinue if occurs), pruritus, chills/fever, GI bleed, peptic ulcer. See literature re: risk of cardiovascular events.

Note:

Formerly known under the brand names Lodine (caps, tabs); Lodine XL (ext-rel tabs).

How Supplied:

Contact supplier.

Indications for Etodolac Tablets:

Pain.

Adult:

Initially 200mg–400mg every 6–8 hrs as needed; usual max 1g/day in divided doses; may increase to 1.2g/day when needed.

Children:

Not recommended.

See Also:

Etodolac Capsules

Contraindications:

Aspirin allergy. Late pregnancy. Coronary artery bypass graft surgery.

Warnings/Precautions:

Discontinue if signs/symptoms of liver disease develop. History of upper GI disease. Asthma. Renal or hepatic impairment. Advanced kidney disease: not recommended. Heart failure. Hypertension. Edema. Bleeding disorders. Monitor blood, hepatic, renal, and ocular function in chronic use. Dehydrated. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Antacids reduce serum levels. Avoid salicylates, phenylbutazone. Monitor anticoagulants, cyclosporine, lithium, digoxin, methotrexate. Renal toxicity may be potentiated with diuretics. May antagonize ACE inhibitors.

Adverse Reactions:

Dyspepsia, GI upset, edema, asthenia/malaise, dizziness, dysuria, urinary frequency, depression, nervousness, renal or hepatic toxicity, rash (discontinue if occurs), pruritus, chills/fever, GI bleed, peptic ulcer. See literature re: risk of cardiovascular events.

Note:

Formerly known under the brand name Lodine.

How Supplied:

Contact supplier.

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