Select therapeutic use:
Indications for Etodolac ext-rel Tablets:
Osteoarthritis. Rheumatoid arthritis.
400mg–1g once daily; max 1.2g/day.
Aspirin allergy. Late pregnancy. Coronary artery bypass graft surgery.
Discontinue if signs/symptoms of liver disease develop. History of upper GI disease. Asthma. Renal or hepatic impairment. Advanced kidney disease: not recommended. Heart failure. Hypertension. Edema. Bleeding disorders. Monitor blood, hepatic, renal, and ocular function in chronic use. Dehydrated. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.
Antacids reduce serum levels. Avoid salicylates, phenylbutazone. Monitor anticoagulants, cyclosporine, lithium, digoxin, methotrexate. Renal toxicity may be potentiated with diuretics. May antagonize ACE inhibitors.
NSAID (pyranocarboxylic acid deriv.).
Dyspepsia, GI upset, edema, asthenia/malaise, dizziness, dysuria, urinary frequency, depression, nervousness, renal or hepatic toxicity, rash (discontinue if occurs), pruritus, chills/fever, GI bleed, peptic ulcer. See literature re: risk of cardiovascular events.
Formerly known under the brand names Lodine (caps, tabs); Lodine XL (ext-rel tabs).