ESTRACE Rx

Select the drug indication to add to your list

ESTRACE

Breast cancer
Menopause and HRT
Prostate and other male cancers
Only 4 drugs may be compared at once

Generic Name and Formulations:

Estradiol 0.5mg, 1mg, 2mg+; scored tabs; +contains tartrazine.

Select therapeutic use:

Indications for ESTRACE:

Palliative treatment of metastatic breast cancer in select patients (see literature).

Adult:

10mg 3 times daily for at least 3 months.

Children:

Not applicable.

Contraindications:

Thrombophlebitis. Thromboembolic disorders. Cerebrovascular disorders. Abnormal undiagnosed genital bleeding. Estrogen-depended neoplasias. Liver dysfunction or disease. Pregnancy (Cat. X).

Warnings/Precautions:

Asthma (2mg tabs). Hepatic dysfunction. Conditions aggravated by fluid retention. Cardiovascular disorders, arterial vascular disease, and risks factors (eg, hypertension, diabetes, obesity, SLE). Familial hyperlipoprotenemia. Monitor BP. Discontinue if jaundice occurs and before prolonged immobilization (eg, surgery). Nursing mothers.

Pharmacological Class:

Estrogen.

Adverse Reactions:

See literature. GI upset, headache, hypertension, edema, hypercalcemia, gallbladder or thromboembolic disease, gynecomastia, impotence, impaired glucose tolerance.

How Supplied:

Tabs—100

ESTRACE 1mg tablets (Qty:30)

appx. price $141.00

Indications for ESTRACE:

Moderate to severe vasomotor symptoms of menopause. Atrophic vaginitis. Hypoestrogenism. Osteoporosis prevention.

Adult:

Menopause, hypoestrogenism: 1–2mg daily, given cyclically (3 weeks on, 1 week off). Osteoporosis prevention (begin therapy soon after menopause): 0.5mg daily for 3 weeks, then stop for 1 week, then recycle; adjust. Reevaluate periodically.

Children:

Not applicable.

Contraindications:

Breast or estrogen-dependent cancer. Thrombophlebitis. Thromboembolic disorders. Undiagnosed abnormal genital bleeding. Pregnancy (Cat.X).

Warnings/Precautions:

Patients with intact uterus should almost always receive a progestin to avoid endometrial hyperplasia. Asthma (2mg tabs). Hepatic dysfunction. Conditions aggravated by fluid retention. Familial hyperlipoproteinemia. Do initial complete physical examination and repeat annually (include BP, mammogram, and PAP smear). Discontinue if jaundice occurs. Nursing mothers.

Pharmacological Class:

Estrogen.

Adverse Reactions:

See literature. Mastodynia, breast secretion, uterine bleeding, dysmenorrhea, amenorrhea, GI upset, headache, hypertension, edema, hypercalcemia, gallbladder or thromboembolic disease, skin changes.

How Supplied:

Tabs—100

ESTRACE 1mg tablets (Qty:30)

appx. price $141.00

Indications for ESTRACE:

Palliative treatment of androgen-dependent advanced prostate cancer.

Adult:

1–2mg 3 times daily.

Children:

Not applicable.

Contraindications:

Thrombophlebitis. Thromboembolic disorders. Cerebrovascular disorders. Abnormal undiagnosed genital bleeding. Estrogen-depended neoplasias. Liver dysfunction or disease. Pregnancy (Cat. X).

Warnings/Precautions:

Asthma (2mg tabs). Hepatic dysfunction. Conditions aggravated by fluid retention. Cardiovascular disorders, arterial vascular disease, and risks factors (eg, hypertension, diabetes, obesity, SLE). Familial hyperlipoprotenemia. Monitor BP. Discontinue if jaundice occurs and before prolonged immobilization (eg, surgery). Nursing mothers.

Pharmacological Class:

Estrogen.

Adverse Reactions:

See literature. GI upset, headache, hypertension, edema, hypercalcemia, gallbladder or thromboembolic disease, gynecomastia, impotence, impaired glucose tolerance.

How Supplied:

Tabs—100

ESTRACE 1mg tablets (Qty:30)

appx. price $141.00