ENTEREG Rx

Indications for ENTEREG:

To accelerate the time to upper and lower gastrointestinal recovery after partial large or small bowel resection surgery with primary anastomosis.

Adult Dose for ENTEREG:

12mg orally 30min to 5 hours before surgery, then 12mg twice daily starting on 1st post-op day for up to 7 days or until hospital discharge (max 15 doses).

Children's Dose for ENTEREG:

Not recommended.

Pharmacological Class:

Opioid antagonist (peripheral).

Contraindications:

Opioid use, at therapeutic doses, for >7 consecutive days prior.

Warnings/Precautions:

For hospital use only. Severe hepatic impairment or end stage renal disease: not recommended. Mild-to-severe renal dysfunction or mild-to-moderate hepatic impairment (monitor; discontinue if adverse reactions occur). Recent (within 1 week) use of more than 3 doses of opioids. Pregnancy (Cat.B). Nursing mothers.

Adverse Reactions:

Dyspepsia, constipation, flatulence, back pain, urinary retention.

Note:

Available only to hospitals that enroll in Entereg Access and Support Program (EASE). For more information, and to enroll, call (866)-4ADOLOR.

How Supplied:

Caps—30