To accelerate the time to upper and lower gastrointestinal recovery after partial large or small bowel resection surgery with primary anastomosis.
12mg orally 30min to 5 hours before surgery, then 12mg twice daily starting on 1st post-op day for up to 7 days or until hospital discharge (max 15 doses).
Opioid antagonist (peripheral).
Opioid use, at therapeutic doses, for >7 consecutive days prior.
For hospital use only. Severe hepatic impairment or end stage renal disease: not recommended. Mild-to-severe renal dysfunction or mild-to-moderate hepatic impairment (monitor; discontinue if adverse reactions occur). Recent (within 1 week) use of more than 3 doses of opioids. Pregnancy (Cat.B). Nursing mothers.
Dyspepsia, constipation, flatulence, back pain, urinary retention.
Available only to hospitals that enroll in Entereg Access and Support Program (EASE). For more information, and to enroll, call (866)-4ADOLOR.