Endometriosis

Elagolix NDA Submitted for Treating Endometriosis-Associated Pain

By September 06, 2017

Elagolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, was evaluated in two Phase 3 clinical studies in about 1,700 women with moderate-to-severe endometriosis-associated pain.

U.S. Patients Lack Awareness of Less Invasive Options for Fibroids

March 07, 2017

Embolization for uterine fibroids may be underused in U.S. hospitals, compared with surgery, according to research presented at the annual meeting of the Society of Interventional Radiology, held from March April 4 to 9 in Washington, D.C.

Positive Results for Elagolix in Two Endometriosis Studies

By October 19, 2016

AbbVie has announced positive results from two replicate Phase 3 clinical trials of Elagolix in premenopausal women with endometriosis.

Study Examines Risks of Colorectal CA Following Oophorectomy

May 16, 2016

Oophorectomy may lead to increased risk of developing colorectal cancer, according to research reported in the June issue of the British Journal of Surgery.

Endometriosis in Young Women Associated With Greater CHD Risks

March 30, 2016

Laparoscopically confirmed endometriosis is associated with increased subsequent risk of coronary heart disease (CHD), according to a study published online in Circulation: Cardiovascular Quality and Outcomes.

Elagolix Demonstrates Efficacy in 2nd Phase 3 Endometriosis Study

By February 10, 2016

AbbVie and Neurocrine Biosciences announced positive top-line results from the second of two replicate Phase 3 clinical trials of Elagolix in premenopausal women with endometriosis-associated pain.

Ureteric Injury Risk With Hysterectomy Varies

August 24, 2015

In 2001 to 2010, 0.5 percent of women experienced ureteric injury in the year after a hysterectomy, with lower rates for benign vs. malignant conditions and rates of injury increasing between 2001 to 2010.

Untreated Pelvic Pain Common Among Women of Reproductive Age

August 13, 2015

Untreated pelvic pain is common among U.S. women in their childbearing years, according to a study published in Human Reproduction.

Drug Likely Culprit in STEMI in Female Patient

By July 29, 2015

Leuprolide, a gonadotropin releasing hormone (GnRH) agonist has been linked to ischemic heart disease and angina in men but a few cases have been reported in women. A case study in Case Reports in Medicine reports on a premenopausal woman with ST elevation myocardial infarction (STEMI) while on leuprolide therapy.

Inpatient vs. Outpatient Uterine Polypectomy: Comparing Costs

May 29, 2015

For women with abnormal uterine bleeding and hysteroscopically diagnosed endometrial polyps, outpatient treatment is more cost-effective than inpatient treatment, according to research published in BJOG: An International Journal of Obstetrics and Gynaecology.

AIUM: Ultrasound Should Be First-Line for Pelvic Imaging

By March 31, 2015

Ultrasound is more cost-effective and safer than other imaging technologies for imaging the female pelvis and it should be the first modality used for patients with pelvic symptoms, advocates of the American Institute of Ultrasound in Medicine (AIUM) have proposed.

Soy Food, Isoflavone Intake Not Linked to Endometrial Cancer

February 09, 2015

Findings in Japanese women aged 45 to 74 years followed during average of 12.1 years

More Coffee May Mean Less Endometrial Cancer Risk

February 06, 2015

Women benefited from drinking about four cups daily

First Study Links Chronic Fatigue Syndrome, Early Menopause

February 06, 2015

Menstrual abnormalities, endometriosis, pelvic pain, hysterectomy, and early/surgical menopause are all associated with chronic fatigue syndrome (CFS), according to new research.

Women May Be Receiving Unnecessary Hysterectomies

January 13, 2015

In many cases, treatments other than hysterectomies could be offered to women with benign gynecologic conditions.

Positive Results for Elagolix in Endometriosis Study

By January 08, 2015

AbbVie announced positive results from one of two ongoing Phase 3 trials for elagolix in premenopausal women with endometriosis.

Laparoscopic Power Morcellators Get Safety Labeling Update

November 24, 2014

The Food and Drug Administration (FDA) is warning against the use of laparoscopic power morcellators in hysterectomy or myomectomy procedures for the majority of women.

Spotting May Be Endometriosis Marker for Women With Infertility

October 17, 2014

Premenstrual spotting for two or more days is associated with endometriosis in women with infertility.

Laparoscopic Uterine Fibroid Removal May Spread Cancer, Says FDA Panel

July 15, 2014

There's no way to guarantee that laparoscopic power morcellation for uterine fibroid removal or hysterectomy won't increase the risk of spreading undetected cancer to other parts of a woman's body, an FDA advisory panel stated.

J&J Halts Sales of Device for Uterine Fibroid Surgery

May 01, 2014

Morcellator sales have been halted due to concerns that use of the device in fibroid removal may worsen undetected uterine sarcoma.

Irregular Menstrual Cycles Possible Marker of Ovarian Cancer Risk

April 10, 2014

Irregular menstrual cycles may be an early marker of ovarian cancer risk.

Pesticide Exposure Linked to Endometriosis Risk

November 05, 2013

Two organochlorine pesticides (OCPs), β-hexachlorocyclohexane (HCH) and mirex, are associated with the risk of endometriosis.

Alcohol Consumption Tied to Endometriosis Risk

August 29, 2013

Alcohol consumption may be associated with an increased endometriosis risk.

Sonogram Best Modality for Diagnosing Ectopic Pregnancy

April 24, 2013

For pregnant women with abdominal pain or vaginal bleeding, transvaginal sonography is the best modality for diagnosing ectopic pregnancy.

Endometriosis Surgery Linked to Lower Ovarian Cancer Risk

April 16, 2013

Women who undergo surgical treatment for endometriosis have a significantly lower risk of developing ovarian cancer.

Gene Variant Linked to Uterine Fibroid Risk

October 08, 2012

A variant of a gene involved in fatty acid synthesis that is often overproduced in cancers is associated with a higher risk of developing uterine fibroids.

Sunscreen Ingredient May Be Linked to Risk of Endometriosis

May 18, 2012

Benzophenone (BP)-type derivatives may be linked to an increased risk of endometriosis.

Endometriosis Linked to Higher Ovarian Cancer Risk

February 22, 2012

A history of endometriosis increases the risk of developing ovarian cancer, although the increased risk is restricted to specific subtypes of invasive ovarian cancer.

Oral Ulipristal Acetate Controls Uterine Fibroid Bleeding

February 02, 2012

For women with symptomatic fibroids, a daily dose of 5mg or 10mg oral ulipristal acetate is efficacious for controlling uterine bleeding before surgery, compared with placebo or leuprolide acetate.