Endocrine Disorders

Noninvasive Marker May ID Severity of Diabetic Retinopathy

January 18, 2018

"Further longitudinal studies seem warranted to determine whether DRIL is a clinically relevant noninvasive morphological marker in eyes with DME," the authors write.

Iodine Deficiency May Impact Fertility in Women of Childbearing Age

January 16, 2018

Those with moderate-to-severe deficiency (iodine-creatinine ratios <50 μg/g) had a 46% reduction in fecundity versus those whose iodine-creatinine ratios were in the adequate range (adjusted fecundability odds ratio of becoming pregnant per cycle, 0.54).

FDA Committee Votes on New Oral Testosterone Replacement Tx

By January 11, 2018

The FDA's Bone, Reproductive and Urologic Drugs Advisory Committee (BRUDAC) voted 6 in favor and 13 against the benefit/risk profile of Tlando (testosterone undecanoate) capsules.

Bydureon BCise Now Available for the Treatment of Type 2 Diabetes

By January 10, 2018

Bydrueon BCise is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Unstable Housing Correlated to Increase in Diabetes-Related ER Visits

January 10, 2018

The researchers found that 13.7% of participants reported a diabetes-related emergency department visit or hospitalization in the previous 12 months.

Ibuprofen Use Linked to Compensated Hypogonadism in Males

By January 09, 2018

For short term ibuprofen use the effects of compensated hypogonadism are reversible, however the researchers state how it is unknown whether these effects are reversible for long-term ibuprofen use.

Bidirectional Links Between Depression, Severe Dysglycemia Evaluated in T1D

January 05, 2018

Depression was strongly associated with increased risk of severe hyperglycemic and hypoglycemic events.

Experts Weigh In on the Best Diets for 2018

By January 03, 2018

DASH and the Mediterranean diet also tied for top stop in the 'Best Diets for Healthy Eating' category will DASH ranked number 1 for the 'Best Heart-Healthy Diets'.

Safety, Tolerability of Dasiglucagon Examined for Severe Hypoglycemia

January 03, 2018

Early pharmacodynamic response for Dasiglucagon were similar to that of GlucaGen, with longer lasting effects plasma glucose.

Microneedle Based Extendin-4 Device Shows Potential for T2D

January 03, 2018

The mechanical strength of alginate-based MN can be enhanced by integration of mineralized particles by crosslinking to facilitate skin penetration.

Cannabidiol Oral Solution Fast Tracked for Rare Pediatric Disorder

By December 27, 2017

The study's primary objectives will be to assess the efficacy of cannabidiol oral solution on hyperphagia-related behavior and body weight in patients with Prader-Willi syndrome

Three New Type 2 Diabetes Treatments Get FDA Approval

By December 26, 2017

Steglatro, Steglujan, and Segluromet have all received FDA approval for the treatment of type 2 diabetes.

FDA Approves Macrilen for Adult Growth Hormone Deficiency Diagnosis

By December 21, 2017

Macimorelin stimulates the secretion of growth hormone from the pituitary gland into the circulatory system.

Pre-Op Liraglutide Examined for Glucose Lowering in Non-Cardiac Sx

December 19, 2017

Liraglutide group had lower median plasma glucose 1 hour postoperatively compared with the insulin infusion and insulin bolus groups.

Microbiome Intervention by Delayed-Release Niacin May Benefit in T2DM

December 18, 2017

"Targeted microbiome intervention by delayed-release NA might represent a future therapeutic option for prediabetes and type 2 diabetes," the authors write.

Can Pharmacist Care in Medical Homes Improve Patient Goals?

December 15, 2017

Researchers found that, compared with the reference group, CPSS patients were 93% more likely to achieve a blood pressure goal <140/90 mm Hg, 57% more likely to achieve hemoglobin A1c values <8%, and 87% more likely to achieve both disease management goals.

'Smart' Insulin Pen System for Humalog, Novolog Available

By December 14, 2017

The InPen is for use with U-100 Lilly Humalog and Novo Nordisk Novolog rapid-acting insulin and indicated for persons aged 12 years and older.

Optimal Glycemic Targets Examined for Short-Term Intensive Insulin Tx

December 14, 2017

Patients in the middle and lower mean blood glucose tertiles had higher 1-year remission rates versus the upper tertile (68.7 and 75% versus 32.3%; both P<0.001).

Generic Equivalent to Kenalog-40 Injection Now Available

By December 12, 2017

Amneal's triamcinolone acetonide is currently the only AP-rated generic equivalent injectable suspension available.

First Short-Acting Insulin Approved as a "Follow-On" Product

By December 11, 2017

The use of abbreviated pathways can reduce drug development costs so products can be offered at a lower price to patients.

Following Gastric Bypass, Nature of &#946;-Cell Sensitivity May Change

December 11, 2017

During the highest dose of glucose infusion, the GB subjects had relative hyperglycemia associated with significantly reduced β-cell glucose sensitivity throughout both step-up

Blood Glucose Lancing Device and Lancets Compatibility

December 07, 2017

Blood Glucose Lancing Device and Lancets Compatibility

Blood Glucose Meter Compatibility with Test Strips

December 07, 2017

Blood Glucose Meter Compatibility with Test Strips chart

Congenital Adrenal Hyperplasia Treatment Granted Orphan Drug Status

By December 07, 2017

CAH is a rare endocrine disorder caused by genetic mutations which result in an inability to produce cortisol.

Intervention Demonstrates Significant T2D Remission in Primary Care

December 06, 2017

A total of 306 individuals aged 20 to 65 years who had been diagnosed with type 2 diabetes in the past 6 years, had a body mass index of 27 to 45kg/m², and were not receiving insulin were recruited.

Ozempic Approved to Treat Adults With Type 2 Diabetes

By December 05, 2017

The global Phase 3a clinical trial program for Ozempic comprised 8 clinical trials involving more than 8,000 adults with type 2 diabetes.

Does Antibiotic Use Increase the Risk of Diabetes?

December 05, 2017

The researchers found that while more cases than controls received at least 6 courses of antibiotics (17.9 versus 13.8%), the association between antibiotic use and risk of diabetes was progressively reduced when clinical and lifestyle factors were accounted for.

T2DM Treatment Adherence Compared Across Drug Classes

December 04, 2017

Adherence better for sulfonylureas and thiazolidinediones compared with metformin

HbA1c-Lowering Effects of DPP4i Therapy May Be Blunted by Diet

December 01, 2017

Multiple regression analyses revealed that fat intake, especially saturated fat intake, was significantly correlated with ΔHbA1c.

Androgens

December 01, 2017

Androgens used for testosterone replacement therapy organized by route of administration chart.