EMCYT Rx

Select the drug indication to add to your list

EMCYT

Prostate and other male cancers
Only 4 drugs may be compared at once

Generic Name and Formulations:

Estramustine phosphate sodium (prodrug of estradiol) 140mg; caps.

Company:

Pfizer Inc.

Select therapeutic use:

Indications for EMCYT:

Palliative of metastatic, progressive prostate cancer.

Adult:

Take 1 hour before or 2 hours after meals. 14mg/kg in 3 or 4 divided doses; reevaluate after 30 to 90 days. Continue as long as favorable response maintained.

Children:

Not applicable.

Contraindications:

Active thrombophlebitis or thromboembolic disorders (except when tumor mass caused by thromboembolic phenomenon). Allergy to estradiol, nitrogen mustard.

Warnings/Precautions:

History of thrombophlebitis, thrombosis, thromboembolic disorders. Cerebro- or cardiovascular disease. Diabetes. Hypertension. Conditions aggravated by fluid retention. Renal or hepatic dysfunction. Monitor bilirubin and hepatic enzymes during and for 2 months after treatment is discontinued. Metabolic bone diseases associated with hypercalcemia. Use effective contraception.

Interactions:

Absorption impaired by calcium.

Adverse Reactions:

Edema, dyspnea, leg cramps; nausea, diarrhea, GI upset; pruritus, dry skin, easy bruising; breast tenderness and enlargement; lethargy, emotional lability, insomnia; leucopenia; abnormal bilirubin, LDH, SGOT. Thrombosis, MI.

How Supplied:

Caps—100

EMCYT 140mg capsules (Qty:6)

appx. price $99.00