EDEX Rx

Indications for EDEX:

Erectile dysfunction.

Adult Dose for EDEX:

Inject over 5–10 seconds into the lateral aspect of the proximal third of the penis, avoid visible veins; rotate injection side and site. Determine optimum dose in office. If no response occurs, may give next higher dose in 1 hour. If partial response occurs, must wait 24 hours before next higher dose. Vasculogenic, psychogenic, or mixed etiology: initially 2.5mcg. If partial response to initial dose, may give 2^nd dose of 5mcg and then may increase by increments of 5–10mcg until desired response achieved. If no response to initial dose, may give 2^nd dose of 7.5mcg and then may increase by increments of 5–10mcg until desired response achieved. Neurogenic etiology: initially 1.25mcg. May give 2^nd dose of 2.5mcg, and 3^rd dose of 5mcg, and then may increase by increments of 5mcg until desired response achieved. Max: 40mcg and 3 self-injections per week; allow at least 24 hours between doses. Reduce dose if erection lasts over 1 hour.

Children's Dose for EDEX:

Not recommended; see Contraindications.

Pharmacological Class:

Prostaglandin.

Contraindications:

Predisposition to priapism. Anatomical penile deformation. Penile implants. Patients for whom sexual activity is inadvisable or contraindicated. Women. Children. Newborns.

Warnings/Precautions:

Treat priapism immediately. Reevaluate every 3 months. Discontinue if penile fibrosis occurs. Renal dysfunction.

Interactions:

Concomitant vasoactive agents: not recommended. Caution with heparin.

Adverse Reactions:

Penile pain, priapism, injection site reactions, penile angulation or fibrosis, hypertension, headache, dizziness, upper respiratory infections, increased risk of blood-borne diseases, others.

How Supplied:

2-cartridge pack (w. 1 inj device & supplies)—1
6-cartridge pack (w. 1 inj device & supplies)—1