Generic Name and Formulations:
Minocycline (as HCl) 50mg, 75mg, 100mg; tabs.
Company:
Medicis Pharmaceuticals Corp
Adjunct in severe acne.
Take on empty stomach with fluids. 200mg once then 100mg every 12 hours; or 100–200mg once then 50mg four times daily.
Take on empty stomach with fluids. <8 years: not recommended. >8 years: 4mg/kg once then 2mg/kg (max 100mg) every 12 hours.
Tetracycline.
Renal or hepatic impairment. Monitor blood, renal and hepatic function in long-term use. Pregnancy (Cat.D), nursing mothers: not recommended.
Antacids, iron, calcium, magnesium, urinary alkalinizers reduce absorption. Avoid penicillins, methoxyflurane. Monitor PT with anticoagulants. May antagonize oral contraceptives.
Dizziness, GI upset, rash, pseudotumor cerebri, blood dyscrasias, increased BUN, interstitial nephritis, hepatotoxicity, tinnitus, tooth discoloration; rare: photosensitivity.
Tabs 50mg, 75mg—100, 1000
100mg—50, 1000
Susceptible respiratory, genitourinary, skin and soft tissue, ear/nose/throat infections.
Take on empty stomach with fluids. 200mg once then 100mg every 12 hours; or 100–200mg once then 50mg four times daily. Syphilis: treat for 10–15 days. Meningococcal carrier state: 100mg every 12 hours for 5 days. Mycobacterium marinum infection: 100mg every 12 hours for 6–8 weeks has been used. Uncomplicated urethral, endocervical, or rectal infection w. C.trachomatis or U. urealyticum: 100mg every 12 hours for at least 7 days. For men: Uncomplicated gonococcal infection (not urethritis or anorectal): 200mg once then 100mg every 12 hours for at least 4 days; urethritis: 100mg every 12 hours for 5 days.
Take on empty stomach with fluids. <8 years: not recommended. >8 years: 4mg/kg once then 2mg/kg (max 100mg) every 12 hours.
Tetracycline.
Renal or hepatic impairment. Monitor blood, renal and hepatic function in long-term use. Pregnancy (Cat.D), nursing mothers: not recommended.
Antacids, iron, calcium, magnesium, urinary alkalinizers reduce absorption. Avoid penicillins, methoxyflurane. Monitor PT with anticoagulants. May antagonize oral contraceptives.
Dizziness, GI upset, rash, pseudotumor cerebri, blood dyscrasias, increased BUN, interstitial nephritis, hepatotoxicity, tinnitus, tooth discoloration; rare: photosensitivity.
Tabs 50mg, 75mg—100, 1000
100mg—50, 1000