DYAZIDE Rx

Select the drug indication to add to your list

DYAZIDE

Edema
Hypertension
Only 4 drugs may be compared at once

Generic Name and Formulations:

Triamterene 37.5mg, hydrochlorothiazide 25mg; caps.

Company:

GlaxoSmithKline

Select therapeutic use:

Indications for DYAZIDE:

Edema.

Adult:

1–2 caps once daily.

Children:

Not recommended.

Contraindications:

Hyperkalemia. Renal impairment. Anuria. Sulfonamide allergy. Concomitant potassium or K+-sparing diuretics.

Warnings/Precautions:

Diabetes. Acidosis predisposition. Electrolyte imbalance. Hypochloremia with metabolic alkalosis. Excess diuresis. History of renal stones. Gout. Surgery. SLE. Monitor electrolytes, renal function. Discontinue if serum potassium >5.5mEq/L or <3mEq/L. Hepatic impairment: monitor for hepatic coma, if confusion increases, discontinue for a few days. Severely ill. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Digoxin, lithium toxicity. Hyperkalemia more likely with ACE inhibitors, parenteral penicillin G. Hypokalemia with ACTH, corticosteroids, amphotericin B. Hyponatremia with sulfonylureas. NSAIDs may cause renal failure. Adjust antidiabetic, antigout medications. May potentiate nondepolarizing muscle relaxants, antihypertensives. Antagonizes oral anticoagulants, methenamine. May interfere with parathyroid tests.

Pharmacological Class:

K+-sparing + thiazide.

Adverse Reactions:

Drowsiness, muscle cramps, weakness, headache, GI disturbances, dizziness, impotence, arrhythmias, hypotension, dry mouth, urine discoloration.

How Supplied:

Caps—100, 1000

DYAZIDE 37.5mg/25mg capsules (Qty:30)

appx. price $68.00

Indications for DYAZIDE:

Hypertension when normokalemia is essential.

Adult:

1–2 caps once daily.

Children:

Not recommended.

Contraindications:

Hyperkalemia. Renal impairment. Anuria. Sulfonamide allergy. Concomitant potassium or K+-sparing diuretics.

Warnings/Precautions:

Diabetes. Acidosis predisposition. Electrolyte imbalance. Hypochloremia with metabolic alkalosis. Excess diuresis. History of renal stones. Gout. Surgery. SLE. Monitor electrolytes, renal function. Discontinue if serum potassium >5.5mEq/L or <3mEq/L. Hepatic impairment: monitor for hepatic coma, if confusion increases, discontinue for a few days. Severely ill. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Digoxin, lithium toxicity. Hyperkalemia more likely with ACE inhibitors, parenteral penicillin G. Hypokalemia with ACTH, corticosteroids, amphotericin B. Hyponatremia with sulfonylureas. NSAIDs may cause renal failure. Adjust antidiabetic, antigout medications. May potentiate nondepolarizing muscle relaxants, antihypertensives. Antagonizes oral anticoagulants, methenamine. May interfere with parathyroid tests.

Pharmacological Class:

K+-sparing + thiazide.

Adverse Reactions:

Drowsiness, muscle cramps, weakness, headache, GI disturbances, dizziness, impotence, arrhythmias, hypotension, dry mouth, urine discoloration.

How Supplied:

Caps—100, 1000

DYAZIDE 37.5mg/25mg capsules (Qty:30)

appx. price $68.00