HCTZ vs. Indapamide and Chlorthalidone: Head-to-Head Trials Reviewed

Thiazide-related diuretics are recommended as first-line treatment in most hypertension guidelines and have been shown to be especially beneficial in resistant and salt-sensitive forms of hypertension. However, there are variations in the properties of thiazide-related medications and few studies have compared hydrochlorothiazide (HCTZ) with the thiazide-like indapamide (INDAP) and chlorthalidone (CTDN) despite the fact that both INDAP and CTDN have been recommended as a replacement for HCTZ.

Nanodevice With Dual Therapy May Help Fight Cancer Drug Resistance

Scientists at the Massachusetts Institute of Technology (MIT) have developed a new nanodevice to block the gene that confers drug resistance and deliver a sustained release of drugs.

Sleep "Debt" Seen in Adults with Stress, Poor Health

According to the 2015 Sleep in America Poll, stress and poor health are key factors in shorter sleep durations and worse sleep quality.

MDs See Reduced Opioid Rx With State Drug Monitoring Programs

In a new survey, nearly 75 percent of physicians believe that state prescription drug monitoring programs have led to a reduction in the prescribing of opioids.

Can Nano "Drones" Help Prevent Heart Attacks, Strokes?

Biodegradable nano drones that deliver a specific healing molecule to fat deposits in arteries may help in preventing heart attacks due to atherosclerosis.

What Will CKD Prevalence be in 2030? New Prediction for Adults Over 30

A new report predicts that the prevalence of chronic kidney disease (CKD) in adults aged 30 and over will rise from the current rate of 13.2 percent to 16.7 percent by 2030.

More Choosing Single Embryo Transfers as IVF Birth Rates Continue to Rise

With drop in number of multiple embryo transfers, twin and triplet birth rates

Safety of APAP Questioned: Is It Time for a New Review?

Researchers call for a new systematic review of acetaminophen's effectiveness and safety

The Link Between Coffee Consumption and Clogged Arteries

Three to five cups daily appears to lower risk

For Obese, Sedentary Patients, Any Exercise Is Beneficial

But only higher intensity exercise lowers blood glucose levels