The risks of metastasis and death associated with cutaneous squamous cell carcinoma are low, but significant, and risk factors for poor outcome include tumor diameter, invasion beyond fat, poor differentiation, and location.
Men's middle-aged fitness level may protect against cancer.
Concurrent use of two immune checkpoint antibodies -- ipilimumab and nivolumab -- may be effective for the treatment of advanced melanoma.
Moderate aerobic exercise prevents fructose-induced hypertriglyceridemia in healthy males.
For patients with major depressive disorder (MDD), exercise is beneficial as monotherapy or as an adjunct therapy.
In patients with inflammatory diseases without diabetes, treatment with low-dose prednisolone has deleterious effects on carbohydrate metabolism.
In middle-aged women, depression is associated with a significantly increased risk of stroke, even after adjustment for lifestyle and physiological variables.
Few randomized clinical trials have been done to assess clinical prediction rules for patients with lower back pain, and the trials that have been done are of low quality and do not provide sufficient evidence to support their use.
Transition of Combivent Respimat is nearly complete as Boehringer Ingelheim plans to cease distribution of Combivent MDI in May.
Up to one-fifth of U.S. children experience a mental disorder, and the prevalence of such disorders appears to be on the rise.