The Food and Drug Administration (FDA) has approved label changes for Olysio (simeprevir; Janssen) to include dosing recommendations for the treatment of hepatitis C virus (HCV)/HIV-1 co-infection, and to expand the indications and usage to include genotype 4 infection.
The U.S. Preventive Services Task Force (USPSTF) recommends colorectal cancer (CRC) screening starting at age 50 years and continuing through age 75 years.
For intensive care unit (ICU) patients with fever due to probable infection, early administration of acetaminophen does not affect the number of ICU-free days.
Upper-limb remote ischemic preconditioning (RIPC) is not beneficial for patients undergoing cardiac surgery, according to two studies published in the New England Journal of Medicine.
The early signs of child abuse among infants and toddlers - head trauma, rib fractures, or abdominal injuries - are often missed, and that may be due in part to a lack of standardized screening.
Surveillance of seven U.S. metropolitan areas found higher-than-expected levels of carbapenem-resistant Enterobacteriaceae (CRE) in Atlanta, Baltimore, and New York City.
For severely disabled patients with central neurological disorders, therapeutic positioning does not appear to affect vital parameters.
Inclusion of the coronary artery calcium (CAC) score improves coronary heart disease (CHD) risk prediction, while the absence of CAC reclassifies many patients as not eligible for statins.
In patients with heart failure with preserved ejection fraction (HFpEF), sodium nitrite infusion favorably reduces exercise-linked hemodynamic derangements of cardiac failure.
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