A mutation has been identified in the gene encoding the transcription factor growth factor independent 1B (GFI1B), which causes gray platelet syndrome.
New guidelines for lipid management in chronic kidney disease (CKD) recommend wider statin use.
In a cohort study of women runners and walkers, less exercise and larger breast cup size were associated with increased mortality from breast cancer.
Narrow-spectrum antibiotics, which are recommended as first-line therapy for children hospitalized with community-acquired pneumonia (CAP), show similar outcomes compared with broad-spectrum antibiotics.
Many patients with myeloproliferative neoplasms without mutations in the Janus kinase 2 gene (JAK2) or in the thrombopoietin receptor gene (MPL) have mutations in the CALR gene encoding calreticulin.
In lung cancer screening, there is a relative mortality reduction with low-dose computed tomography (LDCT); however, limitations include a high rate of overdiagnosis.
Recommendations to effectively address the problem of prescription drug abuse are presented in a policy position paper from the American College of Physicians (ACP).
For patients undergoing spinal procedures, the local application of vancomycin powder in surgical wounds does not significantly reduce the incidence of infection.
In older adults pain is common and is associated with clinically significant declines in physical function.
The FDA has granted Lymphoseek (technetium 99m tilmanocept; Navidea) Injection Fast Track designation for sentinel lymph node detection in patients with head and neck cancer.