≥18yrs: 15mg at bedtime. May reduce to 7.5mg at bedtime after 1–2 days.
<18yrs: not recommended.
Initially 7.5mg at bedtime; may increase to 15mg after 1–2 days.
Sleep apnea. Pregnancy (Cat.X).
Drug or alcohol abuse. Avoid prolonged use. Withdraw gradually. Suicidal tendencies. Depression. Pulmonary, renal, or hepatic disease. Elderly. Debilitated. Nursing mothers: not recommended.
Potentiates CNS depression with alcohol, other CNS depressants. May potentiate CYP2B6 substrates (eg, efavirenz, buproprion); monitor.
CNS depression, complex sleep-related behaviors (eg, sleep-driving), ataxia, headache, dry mouth, GI upset, paradoxical excitement; anaphylaxis, angioedema.