Adjunct in irritable bowel syndrome, enterocolitis, duodenal ulcer.
5–10mL 3–4 times daily.
<10lb (4.5kg): not recommended. 10lb (4.5kg): Initially 0.5mL every 4 hours or 0.75mL every 6 hours. 20lb (9.1kg): 1mL every 4 hours or 1.5mL every 6 hours. 30lb (13.6kg): 1.5mL every 4 hours or 2mL every 6 hours. 50lb (22.7kg): 2.5mL every 4 hours or 3.75mL every 6 hours. 75lb (34kg): 3.75mL every 4 hours or 5mL every 6 hours. 100 lb (45.4kg): 5mL every 4 hours or 7.5mL every 6 hours.
Barbiturate + anticholinergics.
Glaucoma. Porphyria. Unstable cardiovascular status. GI or GU obstruction. Paralytic ileus or intestinal atony. Toxic megacolon. Severe ulcerative colitis. Myasthenia gravis. Hiatal hernia. History of paradoxical reactions to phenobarbital.
Renal or hepatic impairment. Autonomic neuropathy. Cardiovascular disease. Hypertension. Hyperthyroidism. Drug abusers. High environmental temperature. Gastric ulcer. Diarrhea. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers.
Potentiated CNS depression with alcohol, other CNS depressants. Additive anticholinergic effects with other anticholinergics, narcotics, type I antiarrhythmics, antihistamines, phenothiazines, tricyclics. May antagonize anticoagulants, CYP450 substrates.
Drowsiness, anticholinergic effects, paradoxical excitement.
Tabs—100, 1000; Extentabs—100, 500; Elixir—4oz, pt