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DILANTIN

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Generic Name for DILANTIN

Phenytoin sodium 30mg, 100mg; ext-rel caps.

Legal Classification:

Pharmacological Class for DILANTIN

Hydantoin.

Manufacturer of DILANTIN

Pfizer Labs

Indications for DILANTIN

Tonic-clonic, psychomotor and neurosurgically induced seizures.

Adult dose for DILANTIN

Initially: 100mg 3 times daily. Increase weekly if needed; max 200mg 3 times daily. Once-a-day dosing only with ext-rel caps for patients controlled on 300mg daily.

Children's dosing for DILANTIN

Initially 5mg/kg per day in 2–3 equally divided doses. Increase weekly if needed. Usual maintenance: 4–8mg/kg per day; max 300mg daily.

Also:

DILANTIN INFATABS

DILANTIN SUSPENSION

Precautions for DILANTIN

Diabetes. Impaired liver function. Change dose gradually. Discontinue if rash develops. Monitor serum levels. Use proper dental hygiene. Hormonal contraception. Porphyria. Elderly. Debilitated. Pregnancy. Nursing mothers: not recommended.

Interactions for DILANTIN

Potentiated by acute alcohol ingestion, amiodarone, benzodiazepines (eg, diazepam), chloramphenicol, dicumarol, disulfiram, estrogens, fluoxetine, halothane, H₂ blockers, isoniazid, methylphenidate, phenothiazines, phenylbutazone, salicylates, succinamides (eg, ethosuximide), sulfonamides, tolbutamide, trazodone, others. Antagonized by chronic alcohol ingestion, carbamazepine, reserpine, others. Antagonizes tricyclic antidepressants, oral anticoagulants, oral contraceptives, estrogens, corticosteroids, doxycycline, digitoxin, furosemide, theophylline, rifampin, quinidine, vitamins D and K, others. Variable effects with phenobarbital, valproic acid, divalproex, others. Absorption decreased by calcium, antacids.

Adverse Reactions for DILANTIN

Nystagmus, ataxia, slurred speech, decreased coordination, dizziness, GI disturbances, gingival hyperplasia, osteomalacia, blood dyscrasias, lymphadenopathy, hepatic disease, rash, hyperglycemia, SLE, hypertrichosis.

How is DILANTIN supplied?

Caps, Tabs—100
Susp—8oz

Related Disease:

Epilepsy

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