DILANTIN
Generic Name for DILANTIN
Phenytoin sodium 30mg, 100mg; ext-rel caps.
Legal Classification:
Rx
Pharmacological Class for DILANTIN
Hydantoin.
Manufacturer of DILANTIN
Pfizer Labs
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Indications for DILANTIN
Tonic-clonic, psychomotor and neurosurgically induced seizures.
Adult dose for DILANTIN
Initially: 100mg 3 times daily. Increase weekly if needed; max 200mg 3 times daily. Once-a-day dosing only with ext-rel caps for patients controlled on 300mg daily.
Children's dosing for DILANTIN
Initially 5mg/kg per day in 2–3 equally divided doses. Increase weekly if needed. Usual maintenance: 4–8mg/kg per day; max 300mg daily.
Also:
Warnings/Precautions for DILANTIN
Diabetes. Impaired liver function. Change dose gradually. Discontinue if rash develops. Monitor serum levels. Use proper dental hygiene. Hormonal contraception. Porphyria. Elderly. Debilitated. Pregnancy. Nursing mothers: not recommended.
Interactions for DILANTIN
Potentiated by acute alcohol ingestion, amiodarone, benzodiazepines (eg, diazepam), chloramphenicol, dicumarol, disulfiram, estrogens, fluoxetine, halothane, H2 blockers, isoniazid, methylphenidate, phenothiazines, phenylbutazone, salicylates, succinamides (eg, ethosuximide), sulfonamides, tolbutamide, trazodone, others. Antagonized by chronic alcohol ingestion, carbamazepine, reserpine, others. Antagonizes tricyclic antidepressants, oral anticoagulants, oral contraceptives, estrogens, corticosteroids, doxycycline, digitoxin, furosemide, theophylline, rifampin, quinidine, vitamins D and K, others. Variable effects with phenobarbital, valproic acid, divalproex, others. Absorption decreased by calcium, antacids.
Adverse Reactions for DILANTIN
Nystagmus, ataxia, slurred speech, decreased coordination, dizziness, GI disturbances, gingival hyperplasia, osteomalacia, blood dyscrasias, lymphadenopathy, hepatic disease, rash, hyperglycemia, SLE, hypertrichosis.
How is DILANTIN supplied?
Caps, Tabs—100
Susp—8oz
Related Disease:
Epilepsy
Seizure disorders