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DILACOR XR
Angina
Hypertension
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Drug Name:

DILACOR XR Rx

Generic Name and Formulations:
Diltiazem HCl 120mg, 180mg, 240mg; ext-rel caps.

Company:
Actavis

e-Prescribe this drug via Surescripts


Therapeutic Use:

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Indications for DILACOR XR:

Chronic stable angina.

Adult Dose for DILACOR XR:

Do not crush or chew. Take in AM on empty stomach. Initially 120mg once daily. Usual max 480mg once daily. May titrate over 7–14 days.

Children's Dose for DILACOR XR:

Not recommended.

Pharmacological Class:

Calcium channel blocker (benzothiazepine).

Contraindications:

Sick sinus syndrome, 2nd- or 3rd-degree AV block unless paced. Hypotension. Acute MI and pulmonary congestion documented by X-ray on admission.

Warnings/Precautions:

Impaired ventricular, renal or hepatic function. Monitor hepatic function. Discontinue if persistent rash occurs. Preexisting severe gastric stricture. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Digoxin and β-blockers may lead to AV block. Monitor digoxin levels. Serum propranolol, carbamazepine levels may be increased. Potentiation with cimetidine, cyclosporine. Anesthetics may potentiate cardiac depression. Additive hypotensive effects with antihypertensives.

Adverse Reactions:

Pain, rhinitis, GI upset, dizziness, cough, bradycardia, atrial fibrillation, arthralgia, CNS effects, dyspnea.

How Supplied:

Caps—100, 500

Indications for DILACOR XR:

Hypertension.

Adult Dose for DILACOR XR:

Do not crush or chew. Take in AM on empty stomach. Initially 180mg or 240mg once daily. Usual range: 180–480mg/day; max 540mg/day. Over 60 yrs: may start with 120mg daily.

Children's Dose for DILACOR XR:

Not recommended.

Pharmacological Class:

Calcium channel blocker (benzothiazepine).

Contraindications:

Sick sinus syndrome, 2nd- or 3rd-degree AV block unless paced. Hypotension. Acute MI and pulmonary congestion documented by X-ray on admission.

Warnings/Precautions:

Impaired ventricular, renal or hepatic function. Monitor hepatic function. Discontinue if persistent rash occurs. Preexisting severe gastric stricture. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Digoxin and β-blockers may lead to AV block. Monitor digoxin levels. Serum propranolol, carbamazepine levels may be increased. Potentiation with cimetidine, cyclosporine. Anesthetics may potentiate cardiac depression. Additive hypotensive effects with antihypertensives.

Adverse Reactions:

Pharyngitis, cough, flu syndrome, edema, myalgia, GI upset, sinusitis, asthenia, vasodilatation, pain, arthrosis, insomnia, tinnitus, rash; liver abnormalities (rare).

How Supplied:

Caps—100, 500